Results 131 to 140 of about 49,637 (294)
The Effects of Discretionary Fiscal Policy on Macroeconomic Aggregates: A Reappraisal [PDF]
Fiscal stimuli to recover? A cascade of academic and layman-articles debate the effectiveness of fiscal policy in stimulating the economy backed up by different economic models and empirical support.
Hebous, Shafik
core +1 more source
Advanced Science, EarlyView.A new cerebrocortical organoid model using isogenic hiPSCs with familial Alzheimer's mutations recapitulates key AD features, including amyloid‐beta and phospho‐Tau aggregation, neuronal hyperexcitability, and synapse loss. Single‐cell RNA‐seq reveals aberrant pathways in excitatory and inhibitory neurons.
Sergio R. Labra +23 more
wiley +1 more source
Twin deficit hypothesis: evidence from the Turkish economy
, 2012 The Turkish economy has functioned according to the outward-oriented growth model since 24 January 1980, when structural changes and transformation decisions were agreed upon. However, chronic external deficit problems have been encountered since the adoption of the outward-oriented growth model.
openaire +1 more source
Fiscal Policy and Current Account Dynamics in Case of Pakistan [PDF]
The study empirically investigates the effects of fiscal policy or government budget deficit shocks on the current account and the other macroeconomic variable: real output, real interest rate and exchange rate for Pakistan over the period 1960-2009. The
Arif, Umaima +2 more
core +1 more source
Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease
Advanced Science, EarlyView.ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan +17 more
wiley +1 more source
Are the fiscal and monetary policies of the G-7 countries effective in decreasing the U.S. trade deficit? [PDF]
The U.S. trade deficit is a major concern for the G-7 countries. However, it is unclear whether their fiscal and monetary policies are effective in this regard. We examine the relationship between the U.S.
Hideki Nishigaki
core
Advanced Science, EarlyView.Protein restriction (PR) slows Alzheimer's disease (AD) in mice, and other benefits of PR are due to decreased branched‐chain amino acids (BCAAs). We show that restricting any BCAA has benefits, with sex‐ and BCAA‐specific impacts on pathology, molecular signaling, and cognition.
Reji Babygirija +22 more
wiley +1 more source
Bubbles, External Imbalances & Demand for International Liquidity in the Bretton Woods II System [PDF]
Global structural factors both monetary and real played a prominent role in the burst of subprime crisis: 1) the Bretton Woods II international monetary system; 2) the reduction of US real investment return compared with competing countries. We develop a
Andrea Ricci
core
Advanced Science, EarlyView.We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin +17 more
wiley +1 more source
Advanced Science, EarlyView.A retinoic acid receptor agonist, TTNPB, drives the efficient generation of advanced neural stem cells (ANSCs) from human pluripotent stem cells. TTNPB‐centered chromatin remodeling and metabolic reprogramming, promote neuroectoderm commitment. The resulting cells show robust neural potential and functional efficacy in a rat depression model.
Ruilin Du +17 more
wiley +1 more source