Results 151 to 160 of about 49,659 (292)

The determinants of current account imbalances in the Euro Area: a panel estimation approach [PDF]

The purpose of this paper is to explore the main macroeconomic, financial and structural factors that influenced current account developments in the euro area countries over the period from 1980 to 2008.
Brissimis, Sophocles, Hondroyiannis, George, Papazoglou, Christos, Tsaveas, Nicholas, Vasardani, Melina   +4 more
core   +1 more source

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

Advanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto, Tristan Dellazizzo Toth, Silvano Bond, Alexander Schmitz, Rim Diab, Sara Y. Ngo Tenlep, Brian Mooney, Silvia Erni, Martina Schobesberger, Olivier Scheidegger, Camille Peitsch, Smita Saxena   +11 more
wiley   +1 more source

Dermatoglyphics and schizophrenia: A comprehensive review of neurodevelopmental biomarkers. [PDF]

World J Psychiatry
Bou Farah E, Beydoun K, Nasr L, Chokor Z, Ghanem S, El Fassih I, Akiki S, Moghnieh R, Tlaiss Y, Farhat H.   +9 more
europepmc   +1 more source

The Evolutionarily Conserved TPM1 Super‐Enhancer Drives Skeletal Muscle Regeneration via Mechanotransduction Signaling

Advanced Science, EarlyView.
By integrating biomechanical and epigenetic cues, the evolutionarily conserved TPM1 super‐enhancer drives myogenesis via TEAD4‐mediated chromatin looping. This mechanism produces species‐specific outputs (linear TPM1 mRNA in mice and CircTPM1 in bovine) that activate PI3K/AKT mechanotransduction and the MYH10/MYL3 axis to execute cytoskeletal ...
Ruimen Zhang, Wanyou Feng, Yanyan Yang, Yu Pan, Chaoxia Zou, Leyi Wang, Sanbao Zhang, Yimin Zhao, Yongmei Wu, Jinling Wang, Jianwei Zou, Kehe Cen, Yongwang Zhang, Han Huang, Yurong Xu, Li Zhong, Hailong Gong, Juanru Cheng, Jingyuan Liang, Zihua Zheng, Qinyang Jiang, Jingwei Wei, Hui Li, Minhui Liang, Deshun Shi, Sufang Yang, Yanfei Deng, Yingming Wei   +27 more
wiley   +1 more source

Supplementation with Polyphenols (Olive and Grape Extracts) Improves Pregnancy Outcomes in Underfed Sheep. [PDF]

Antioxidants (Basel)
Pesántez JL, Martínez-Ros P, González-Bulnes A, López-Mendoza MC, Sales F, Hashem NM, Reyes ML, Raggi LA, Yeste-Vizcaíno N, Parraguez VH.   +9 more
europepmc   +1 more source

Deficits and the Economy: All Deficits Are Not Created Equal [PDF]

Recent academic and popular discussions of budget deficits rely upon a simplistic and, in large part, false conception of their effects. The recent literature ignores the fact that deficit effects depend on their source and on private sector responses to
Tatom, John
core   +1 more source

Multimodal Optical Imaging and Modulation with Simultaneous Electrophysiology Through Smart Dura in Non‐Human Primates

Advanced Science, EarlyView.
This study demonstrates multimodal integration in non‐human primates, combining large‐scale, high‐density electrophysiology using Smart Dura with optical techniques such as multiphoton imaging (MPI), photothrombotic lesioning, optical coherence tomography angiography (OCTA), wide‐field intrinsic signal optical imaging (ISOI), and optogenetics.
Nari Hong, Sergio Montalvo Vargo, Gaku Hatanaka, Zhaoyu Gong, Noah Stanis, Jasmine Zhou, Tiphaine Belloir, Ruikang K. Wang, Wyeth Bair, Maysamreza Chamanzar, Azadeh Yazdan‐Shahmorad   +10 more
wiley   +1 more source

About Unsuccessful Responders to Diet and Physical Activity Interventions: A Focus on Energy Balance and Body-Weight Loss. [PDF]

Nutrients
Tremblay A, Jacob R, Pérusse L, Drapeau V.   +3 more
europepmc   +1 more source

Autophagy Activators Normalize Aberrant Tau Proteostasis and Rescue Synapses in Human Familial Alzheimer's Disease iPSC‐Derived Cortical Organoids

Advanced Science, EarlyView.
A new cerebrocortical organoid model using isogenic hiPSCs with familial Alzheimer's mutations recapitulates key AD features, including amyloid‐beta and phospho‐Tau aggregation, neuronal hyperexcitability, and synapse loss. Single‐cell RNA‐seq reveals aberrant pathways in excitatory and inhibitory neurons.
Sergio R. Labra, Jadon Compher, Akhil Prabhavalkar, Mireya Almaraz, Claudia Cedeño Kwong, Christine Baal, Maria Talantova, Nima Dolatabadi, Julian Piña‐Sanz, Yubo Wang, Leonard Yoon, Swagata Ghatak, Zi Gao, Yuting Zhang, Dorit Trudler, Lynee Massey, Wei Lin, Anthony Balistreri, Michael Bula, Nicholas J. Schork, Tony S. Mondala, Steven R. Head, Jeffery W. Kelly, Stuart A. Lipton   +23 more
wiley   +1 more source

Cognitive, neuroimaging, and genetic insights on the interthalamic adhesion from a large cohort study of 591 subjects. [PDF]

Sci Rep
Vidal JP, Gouarderes A, Rabenantenaina MS, Péran P, Pariente J, Danet L, Barbeau EJ.   +6 more
europepmc   +1 more source