Results 201 to 210 of about 2,051,163 (245)

TAB2 Causes Neuronal Damage by Aggravating Microglia‐Mediated Neuroinflammation in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
In microglia, STAT3 upregulates TAB2, which promotes NF‐κB activation through its NZF domain‐mediated recognition of K63‐linked ubiquitin chains, leading to inflammatory cytokine release and subsequent neuronal injury. Lumacaftor suppresses TAB2 expression and directly binds the TAB2‐NZF domain to interrupt K63 ubiquitin recognition, thereby blocking ...
Yanhao Zhao   +12 more
wiley   +1 more source

Lifespan normative modeling of brain microstructure. [PDF]

open access: yesNat Commun
Villalón-Reina JE   +19 more
europepmc   +1 more source

Graphene‐Engineered Rear Interfaces Enable Efficient Flexible CZTSSe Solar Cells on Metal Foils

open access: yesAdvanced Science, EarlyView.
An atomically thin graphene interlayer stabilizes the rear interface of flexible CZTSSe solar cells by regulating interfacial stress, suppressing detrimental interfacial reactions, and reducing the back‐contact barrier. This strategy simultaneously improves photovoltaic performance and mechanical durability.
Yixiong Ji   +18 more
wiley   +1 more source

Advances in Se Wide‐Bandgap Photovoltaics and TexSe1‐x SWIR Photodiodes

open access: yesAdvanced Science, EarlyView.
In this review, fundamental properties and current challenges in Se photovoltaics (PVs) for tandem and indoor PVs and TexSe1‐x alloys for short wave infrared photodiodes are discussed. A case is made for the practicality of elemental chalcogenide optoelectronics, and a pathway toward resolving the key challenges in these respective technologies is ...
Adam D. Alfieri, Deep Jariwala
wiley   +1 more source

A Word About Hypothesis

open access: yes, 2008
Hypothesis Editors-in-Chief
core   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

open access: yesAdvanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang   +10 more
wiley   +1 more source

Mechanical stability of the interaction between a lower-limb rehabilitation exoskeleton and the user's body during functional tasks. [PDF]

open access: yesFront Bioeng Biotechnol
Squartecchia S   +8 more
europepmc   +1 more source

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