Results 51 to 60 of about 1,043,093 (335)

Globalization and social inequalities in Europe: assessment and outlook [PDF]

Eastern Journal of European Studies, 2012
The purpose of this article is to consider the social cohesion of the European Union which is today subjected to significant constraints by globalization and by the growing economic divergence between member States, especially in the Euro zone.
Hannah Brady, Bernard Yvars, Carmela MALTONE   +2 more
doaj  

Case Report: A Case Study on the Neurodevelopmental Profile of a Child With Pallister–Killian Syndrome and His Unaffected Twin

Frontiers in Pediatrics, 2022
Pallister–Killian syndrome is an uncommon genetic disorder that has broad developmental and multisystemic effects. While medical complications are widely reported throughout the literature, research on the neurodevelopmental profile has been limited ...
Carole A. Samango-Sprouse, Carole A. Samango-Sprouse, Carole A. Samango-Sprouse, Mary P. Hamzik, Kenneth Rosenbaum, Kosar Khaksari, Francie Mitchell, Ritika Kommareddi, Michaela R. Brooks, Elizabeth Tipton, Teresa Sadeghin, Andrea L. Gropman, Andrea L. Gropman   +12 more
doaj   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Consequences of fiscal deficit and public debt in financing the public sector [PDF]

Ekonomika Poljoprivrede (1979), 2014
The aim of this paper is to highlight the important issues of the budget deficit and public debt and their impact on economic growth. This paper considers the twin deficit hypothesis, which argues that there is a strong correlation between the current ...
Tešić Aleksandra, Ilić Dragan, Đelić Tanja Anastazija   +2 more
doaj   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Literacy and mental disorders [PDF]

, 2006
Purpose of review: This review examines recent evidence on the comorbidity between literacy problems and psychiatric disorder in childhood and discusses possible contributory factors.
Angold, Arnold, Banaschewski, Barbara Maughan, Byrne, Carroll, Craig, Gayan, Grigorenko, Hechtman, Hinshaw, Julia Carroll, Loo, Lyytinen, Maag, Miller, Nation, Neale, Oliver, Rabiner, Reynolds, Rhee, Shaywitz, Singer, Spira, Stevenson, Trzesniewski, Vellutino, Willcutt, Willcutt   +29 more
core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Anxiety-related experience-dependent white matter structural differences in adolescence: A monozygotic twin difference approach

Scientific Reports, 2017
Anxiety is linked to deficits in structural and functional connectivity between limbic structures and pre-frontal cortices. We employed a monozygotic (MZ) twin difference design to examine the relationship between structural characteristics of the ...
Nagesh Adluru, Zhan Luo, Carol A. Van Hulle, Andrew J. Schoen, Richard J. Davidson, Andrew L. Alexander, H. Hill Goldsmith   +6 more
doaj   +1 more source

Twin Deficit Phenomena in the Two Government Eras in Indonesia

Jurnal Analisis Bisnis Ekonomi, 2020
The aim of this study is to analyze the development of the budget deficit and current account deficit in Indonesia in the era of President SBY and President Jokowi and to compare between the two eras.
Muhammad Ghafur Wibowo
doaj   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source