Results 201 to 210 of about 1,984,424 (229)

Low birth weight, DNA methylation patterns in cord blood, and inflammation at birth. [PDF]

Transl Pediatr
Hou N, Hai L, Jiao Y, Liu A, Chen X, Huang H.   +5 more
europepmc   +1 more source

Nrsn1–Smarcc1 Coupling Regulates Neural Stem Cell Differentiation and Chronic‐phase Recovery After Ischemic Stroke

Advanced Science, EarlyView.
In the post‐stroke brain, Foxa2 induces the transcriptional upregulation of Nrsn1 in NSCs. Nrsn1 functionally couples with Smarcc1, modulating its nuclear availability and protein abundance, thereby influencing Smarcc1‐associated regulatory programs linked to neuronal lineage commitment. Through this coupling, Nrsn1 promotes the differentiation of NSCs
Ruolin Zhang, Chang Liu, Yuneng Zhou, Kaichen Zhao, Muyang Li, Bingcheng Cai, Ying Wang, Zhiyuan Yuan, Zhaoxin Liu, Zilong Yuan, Yao Xiao, Peiyang Zhou, Ke Shui, Wendai Bao, Min Zhang, Jun Qin, Jun Chen, Xin Yang, Zhiqiang Dong   +18 more
wiley   +1 more source

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

Advanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen, Ying Ma, Lixuan Huang, Xin Chen, Fanliang Kong, Zhenzhou Qian, Mingyue Guan, Xinlin Wang, Yanyan Yang, Shasha Zhang, Peng Li, Renjie Chai   +11 more
wiley   +1 more source

Urban exposures, frailty, and mental illness in World Trade Center Health Program responders. [PDF]

Nat Commun
Krasnov H, Hung W, Knobel P, Kloog I, Ko F, Thompson H, Colicino E, Teitelbaum SL, Just AC, Yitshak-Sade M.   +9 more
europepmc   +1 more source

Computational Modeling of Parkinson's Disease Across Scales: From Mechanisms to Biomarkers, Drug Discovery, and Personalized Therapies. [PDF]

Brain Sci
Nair SS, Guha A, Chakravarthy S, Shaikh AG.   +3 more
europepmc   +1 more source

Shared genetics between ADHD and reading/language abilities: Genome-wide correlations, stratified enrichment, cross-trait association, and mendelian randomization. [PDF]

JCPP Adv
Zhao J, Huang S, Liu W, Wang F, Qian H, Hu X.   +5 more
europepmc   +1 more source

Procognitive effects of methyl 2-amino-3-methoxybenzoate (or daopine) may involve the dorsal striatal anthranilic acid pathway and mutimetabolite-multitarget pharmacology. [PDF]

Behav Pharmacol
Bright Y, Amatdjais-Groenen HIV, Verheij MMM, van den Broek PHH, Spoelder M, Maas D, Greupink R, Martens GJM, Homberg JR.   +8 more
europepmc   +1 more source

A comprehensive overview of the biological foundations of ADHD. [PDF]

Biosci Rep
Folego-Temoteo I, Lima YC, Grevet EH, Vidor MV, de A Tavares ME, da Silva BS, Bau CHD, Rovaris DL.   +7 more
europepmc   +1 more source

Targeting Sleep to Improve Outcomes in Psychosis: Digital and Non-Pharmacological Interventions. [PDF]

Medicina (Kaunas)
Baldini V, Gnazzo M, Varallo G, De Ronchi D, Pelizza L, Menchetti M, Plazzi G.   +6 more
europepmc   +1 more source