Results 141 to 150 of about 786,616 (263)

Stress Hyperglycemia Drives CD4+ T Cell PANoptosis and Postoperative Organ Injury via Monocyte‐Derived Succinate

Advanced Science, EarlyView.
High glucose is linked to reduced succinate dehydrogenase activity in CD14+ monocytes, accompanied by succinate accumulation and extracellular release. Extracellular succinate exacerbates mitochondrial ROS production and mtDNA release in CD4+ T cells. Cytosolic mtDNA then activates Z‐DNA binding protein 1 (ZBP1) and engages ZBP1‐associated inflammatory
Shuai Zhao, Xuemei Miao, Wei Luo, Tao Liu, Yang Wang, Jiaying Li, Di Fu, Weiyun Shen, Yan Luo, Kang Chen, Ruping Dai, Hui Li   +11 more
wiley   +1 more source

Maternal Exercise Rescues Embryonic Osteogenesis Impaired due to POLG Mutation Through a Potential Apelin‐ATF4 Axis

Advanced Science, EarlyView.
Maternal exercise (ME) increases apelin abundance across maternal and fetal tissues and is associated with improved fetal osteogenesis under POLG mutation‐induced mitochondrial dysfunction. Apelin‐APJ signaling is linked to enhanced mitochondrial function, Akt phosphorylation, and ATF4‐RUNX2 association, supporting coordinated fetal bone remodeling ...
Song Ah Chae, Ryan C. Riddle, Zhihua Jiang, Chaeyoung Shin, Min Du, Jun Seok Son   +5 more
wiley   +1 more source

Discordant Manifestation of Congenital Heart Block in a Twin Pregnancy: A Case Report. [PDF]

Diagnostics (Basel)
Korpás KL, Török O, Deli T, Beke L, Kovács-Pászthy B, Horváth Á, Orosz L, Méhes G.   +7 more
europepmc   +1 more source

m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress

Advanced Science, EarlyView.
Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang, Ye‐Xin Luo, Cheng‐Fang Sun, Rui Pan, Yu‐Xi Wu, Zhi Yuan, Xin‐Run Wang, Xu‐Dong Zhang, Lan‐Lan Wu, Xiang‐Yu Yao, Zhan‐Dong Song, Wei Chang, Tian Wei, Pan‐Yuan Cai, Tian‐Ci Zhang, Yong‐Wei Xiong, De‐Xiang Xu, Hua Wang, Hua‐Long Zhu   +18 more
wiley   +1 more source

Twin pregnancy in Lusaka

, 1980
Twin pregnancy attending the University Teaching Hospital (U.T.H.), Lusaka.Cases of twin pregnancy attending the University Teaching Hospital (U.T.H.), Lusaka, are analysed. The incidence was one case per 62.
O'Dowd, M. J.
core   +1 more source

Nurse-Led Care: A Case Report of Twin Pregnancy Complicated by Ureteral Calculus and Thyrotoxicosis. [PDF]

J Clin Med
Yu Q, Shi R, Li Y, Na R, Cai X.
europepmc   +1 more source

Pregnancy at work: a national survey

, 2011
The aim of this study is to fill the gap in knowledge around women’s experiences in paid work in Ireland during pregnancy and after childbirth using data from the first nationally representative survey of mothers.
Russell, Helen, Watson, Dorothy, Banks, Joanne   +2 more
core  

Single‐Cell Profiling Reveals a Protective WNT5A‐ATF3‐FOSB Signaling Axis in Hair Follicle Stem Cells During Androgenetic Alopecia

Advanced Science, EarlyView.
Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo, Ke Fang, Changjiang Zhao, Jiachao Xiong, Yuan Zhu, Mingyang Lu, He Yan, Zihan Li, Baojin Wu, Hua Jiang, Yufei Li   +10 more
wiley   +1 more source

Transient Osteoporosis of Bilateral Knee Joints in Twin Pregnancy: A Case Report - A Valuable Addition to the Medical Literature. [PDF]

J Orthop Case Rep
Azaharhussain M, Krishnamurthy SL, Kumar YK, Krishna JBV, Gowda MP.   +4 more
europepmc   +1 more source

Pregnancy discrimination in the workplace: legal framework and review of legal decisions 1999 to 2008

, 2011
The experience of being in employment while pregnant or returning to work after having a child is not well researched in Ireland or indeed internationally.
Russell, Helen, Banks, Joanne
core