Results 51 to 60 of about 786,616 (263)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Teenage pregnancy in the United Kingdom: A behavioral ecological perspective [PDF]

, 2012
In this paper we describe teenage pregnancy and motherhood in the United Kingdom. This has been regarded as a key social policy issue for some time and is the focus of policy intervention under the current administration.
Chipman, Abby, Dickins, Thomas E., Johns, Sarah E.   +2 more
core   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Twin Reversed Arterial Perfusion: To Treat or Not? [PDF]

Journal of Clinical and Diagnostic Research, 2017
Acardiac twinning or Twin Reverse Arterial Perfusion (TRAP)-sequence is a rare complication of monochorionic twin pregnancy. Whether to start elective or therapeutic treatment in TRAP-sequence is still controversial.
Sunita Dubey, Meesha Verma, Poonam Goel, RPS Punia   +3 more
doaj   +1 more source

Twin reversed arterial perfusion syndrome in a monochorionic monoamniotic twin pregnancy

Taiwanese Journal of Obstetrics & Gynecology, 2021
Objective: Twin-Reversed Arterial Perfusion (TRAP) sequence is a rare complication of monochorionic multiple gestation. Conservative management should be considered if there is no poor prognostic factor.
Yi-Yan Chen, Chien-Chu Huang, Chih-Yi Yang, Tsan-Hung Chiu, Ming Ho   +4 more
doaj   +1 more source

Quality of Antenatal Care in Rural Tanzania: Counselling on Pregnancy Danger Signs. [PDF]

, 2010
\ud The high rate of antenatal care attendance in sub-Saharan Africa, should facilitate provision of information on signs of potential pregnancy complications.
Pembe, Andrea B,, Carlstedt, Anders,, Carlstedt Anders, Andrea B Pembe, Darj, Elisabeth, Pembe, Andrea Barnabas,, Gunilla Lindmark, Darj Elisabeth, Pembe, Andrea Barnabas, Urassa, David P,, Carlstedt, Anders, Urassa, David P, Nyström Lennarth, Carlstedt, A., Urassa David P, Darj, Elisabeth,, Lindmark, Gunilla, Carlstedt, A,, Lindmark, Gunilla,, Lindmark, G,, Anders Carlstedt, Lindmark, G., Darj, E., Nyström, Lennarth,, Pembe, Andrea B, Lindmark Gunilla, Nyström, Lennarth, Pembe Andrea B, Urassa, David Paradiso, Urassa, D.P., Urassa, David Paradiso,, Pembe, A.B., David P Urassa, Elisabeth Darj, Nyström, L., Nyström, L,, Lennarth Nyström   +36 more
core   +2 more sources

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Maternal and Perinatal Outcome in Twin Pregnancy

Journal of Nobel Medical College
Background: The incidence of twin pregnancy has significantly risen over past decade along with the use of various assisted reproductive technologies.
Pratibha Kaphle, Gehanath Baral, Amar Nath Chaudhary, Sandeep Acharya   +3 more
doaj   +1 more source

Does a Twin Pregnancy Have a Greater Impact on Physical and Emotional Well‐Being than a Singleton Pregnancy?

, 1995
A prospective, population-based study was conducted to assess the impact of twin pregnancy on a woman's physical and emotional well-being. It compared women's reports of their general health, experience of a range of specific symptoms, and emotional well-
Trudy Goodenough, Karen Thorpe, Thorpe, K, Greenwood, Rosemary, Goodenough, Trudy, Goodenough, T, Greenwood, R, Thorpe, Karen, Rosemary Greenwood   +8 more
core   +1 more source