Results 51 to 60 of about 133,563 (305)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Twin Reversed Arterial Perfusion: To Treat or Not? [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Acardiac twinning or Twin Reverse Arterial Perfusion (TRAP)-sequence is a rare complication of monochorionic twin pregnancy. Whether to start elective or therapeutic treatment in TRAP-sequence is still controversial.
Sunita Dubey   +3 more
doaj   +1 more source

Twin reversed arterial perfusion syndrome in a monochorionic monoamniotic twin pregnancy

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2021
Objective: Twin-Reversed Arterial Perfusion (TRAP) sequence is a rare complication of monochorionic multiple gestation. Conservative management should be considered if there is no poor prognostic factor.
Yi-Yan Chen   +4 more
doaj   +1 more source

Twin Pregnancy in a Woman with Uterus Didelphys [PDF]

open access: yes, 2011
Uterus didelphys is one of the congenital uterine anomalies due to defective medial fusion of mullerian ducts. This anomaly is known to have poor reproductive outcome and women with this condition often have to be treated for infertility.
Bhattacharya, Sohini   +1 more
core   +1 more source

Myomectomy as a pregnancy-preserving option in the carefully selected patient [PDF]

open access: yes, 2002
Objectives: To present the indications for myomectomy during pregnancy and to discuss complications possibly related and unrelated to the procedure. Method and Results: A 33-year-old patient at 18 weeks of gestation underwent removal of a 1,570-gram ...
Baretton, G.   +6 more
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Prevalence and adverse outcomes of twin pregnancy in Eastern Africa: a systematic review and meta-analysis

open access: yesBMC Pregnancy and Childbirth
Introduction Multiple pregnancies are much more common today than they were in the past. Twin pregnancies occur in about 4% of pregnancies in Africa. Adverse pregnancy outcome was more common in twin pregnancy than in singleton pregnancy.
Tamirat Getachew   +11 more
doaj   +1 more source

Selective feticide reverses intrahepatic cholestasis of pregnancy in twins discordant for growth: A case report

open access: yesCase Reports in Women's Health, 2023
Twin gestations are associated with an increased risk of intrahepatic cholestasis in pregnancy (ICP), probably attributed to the elevated pregnancy hormones. We report a case of a dichorionic diamniotic twin pregnancy, at the third trimester, complicated
Kyriaki Mitta   +7 more
doaj   +1 more source

CASE REPORT: Chorangiophagus Parasiticus: A Rare Case Report [PDF]

open access: yes, 2012
Malformations are common in twin pregency compared to singleton pregnancy. One such rare anomaly is Chorangiophagus parasiticus also known as twin to twin transfusion which is an asymmetric abnormality of monozygotic twins, where asymmetric twin survive ...
C. Panduranga   +3 more
core  

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