Results 81 to 90 of about 40,062 (265)

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Comparing pregnancy outcomes in a population with natural versus surgical reduction of twin pregnancies: a retrospective cohort study

Frontiers in Endocrinology
ObjectiveTo compare the cycle of initial twin pregnancy with vanishing twin syndrome (VTS), the cycle of initial twin pregnancy after surgical reduction, and the live birth outcome of initial singleton pregnancy.
Yuanxue Jing, Yuanxue Jing, Jiawei Gao, Xuzhao Gu, Yi Wan, Xiaoxia He, Xiaoxia He, Xiaoling Ma, Xiaoling Ma, Haofei Shen, Haofei Shen   +10 more
doaj   +1 more source

A double dilemma: treatment of stage IV fetal twin-twin transfusion syndrome in the setting of maternal recurrent venous thromoembolism: a case report

BMC Pregnancy and Childbirth, 2019
Background Fetal conditions can pose significant challenges in the management of pregnancies complicated by pre-existing maternal medical conditions. Case presentation We report a case of a 34-year-old woman with Stage IV Twin Twin Transfusion syndrome ...
Claire M. McCarthy, Alya al-Madhani, Suzanne Smyth, Nóirín E. Russell, Ruwan Wimalasundera, Keelin O’Donoghue   +5 more
doaj   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

Association between adverse obstetric history and perinatal outcomes in singleton and twin pregnancies: a retrospective study

Frontiers in Medicine
ObjectiveThis study aimed to understand how adverse obstetric history affects perinatal outcomes in singleton and twin pregnancies, and to determine whether a twin pregnancy is a risk factor for adverse outcomes among women with an adverse obstetric ...
Wei-Zhen Tang, Wei-Zhen Tang, Xia Li, Xia Li, Hong-Yu Xu, Hong-Yu Xu, Qin-Yu Cai, Qin-Yu Cai, Ni-Ya Zhou, Ni-Ya Zhou, Yi-Fan Zhao, Hao-Wen Chen, Hao-Wen Chen, Yue Tang, Fei Han, Fei Han, Tai-Hang Liu, Tai-Hang Liu, Kai Ye, Kai Ye   +19 more
doaj   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Twin versus singleton pregnancies: the incidence, pregnancy complications, and obstetric outcomes in a Nigerian tertiary hospital

International Journal of Women's Health, 2011
NJ Obiechina1, VE Okolie1, GU Eleje1, ZC Okechukwu1, OA Anemeje21Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital (NAUTH), Nnewi, Anambra State, Nigeria; 2Department of Family Medicine, Nnamdi Azikiwe University ...
Obiechina NJ, Okolie VE, Eleje GU, Okechukwu ZC, Anemeje OA   +4 more
doaj  

Prenatal Factors Influencing Calf Morbidity and Mortality in Dairy Cattle: A Systematic Review of the Literature (2000–2024)

Animals
This study aimed to systematically review the literature of the last 24 years to determine the influence of dam heat stress, nutrition, body condition, vaccination, parity, and twin pregnancy on calf morbidity and mortality.
Lukas Trzebiatowski, Frederike Wehrle, Markus Freick, Karsten Donat, Axel Wehrend   +4 more
doaj   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source