Results 151 to 160 of about 10,503 (288)

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Building a Human Digital Twin (HDTwin) Using Large Language Models for Cognitive Diagnosis: Algorithm Development and Validation. [PDF]

JMIR Form Res
Sprint G, Schmitter-Edgecombe M, Cook D.
europepmc   +1 more source

Rare immune diseases paving the road for genome editing-based precision medicine. [PDF]

Front Genome Ed, 2023
Pavel-Dinu M, Borna S, Bacchetta R.
europepmc   +1 more source

Complete Proof of the Twin Prime Conjecture within the Unified Metabolic Causal Field

Jianbing Zhu
openalex   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Digital twin simulations with a micro-multiphysics agent-based model reveal key drivers of bone loss after denosumab discontinuation. [PDF]

Front Bioeng Biotechnol
Ledoux C, Kendall JJ, Boaretti D, Müller R, Collins CJ.   +4 more
europepmc   +1 more source

Decryption speed up of ElGamal with composite modulus. [PDF]

PLoS One, 2020
Kim G, Li S.
europepmc   +1 more source

Usability Testing an mHealth Program with Tailored Motivational Messages for Early Adolescents. [PDF]

Nutrients, 2023
Lin CA, Vosburgh KL, Roy D, Duffy VB.
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Gene Therapy Techniques and Delivery Methods (Review). [PDF]

Sovrem Tekhnologii Med
Shchukina EI, Mazunin IO, Eremin II, Moskalev AA.   +3 more
europepmc   +1 more source