Results 181 to 190 of about 10,503 (288)

Epigenetics in evolution and adaptation to environmental challenges: pathways for disease prevention and treatment. [PDF]

Epigenomics
Abdolmaleky HM, Nohesara S, Zhou JR, Thiagalingam S.   +3 more
europepmc   +1 more source

Twin Prime Numbers, Bounded Gaps Between Primes

, 2015
I.F.M.M. Nelen
openalex   +1 more source

A Poisson Limit Model for Twin Primes via Multi-Residue Sieve Spacings

Fernando Portela
openalex   +1 more source

Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew, Maryam Kargaran, Maik Rothe, Andreas Deistung, Dietrich Stoevesandt, Walter A. Wohlgemuth, David Strube, Thomas Kendzierski, Anna Katharina Kölsch, Maurits Gerhard Abraham Heuschen, Markus Otto, Alexander Mensch   +11 more
wiley   +1 more source

Cell-context response to germ layer differentiation signals is predetermined by the epigenome in regionalized epiblast populations. [PDF]

Nat Commun
Menezes NA, Peterson KJ, Guo X, Castiglioni V, Kalvisa A, Filimonow K, Schachter K, Schuh CM, Pasias A, Mariani L, Brickman JM, Sedzinski J, Ferretti E.   +12 more
europepmc   +1 more source

Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication. In this study, we investigated whether acoustic measures could objectively measure speech dysfunction and identify
Zena Fadel, Charlotte Hennessey, Hannah Lee, Pia Parekh, Sheng‐Han Kuo, Ami Kumar   +5 more
wiley   +1 more source

Crystal structures of <i>trans</i>-di-bromido-bis-(4-picoline)gold(III) tetra-bromido-aurate(III) nitro-methane monosolvate, bis-(2-picolinium) tetra-bromido-aurate(III) bromide, and five salts of the type picolinium or lutidinium tetra-halogenidoaurate(III). [PDF]

Acta Crystallogr E Crystallogr Commun
Döring C, Jones PG.
europepmc   +1 more source

Fractal Invariance and Informational Symmetry in Prime Subsets: A Comparative Study of Sophie Germain and Twin Primes

Paulo Ricardo Laux
openalex   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Mechanistic and structural studies reveal NRAP-1-dependent coincident activation of NMDARs. [PDF]

Cell Rep
Goodell DJ, Whitby FG, Mellem JE, Lei N, Brockie PJ, Maricq AJ, Eckert DM, Hill CP, Madsen DM, Maricq AV.   +9 more
europepmc   +1 more source