Results 171 to 180 of about 785,061 (339)

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Cohort profile and representativeness of participants in the Danish monozygotic twin study on migraine. [PDF]

Eur J Epidemiol
Olofsson IA, Olesen J, Christensen K, Hoffmann ER, Hansen TF.   +4 more
europepmc   +1 more source

Testing Putative Causal Associations of Risk Factors for Early Intercourse in the Study of Twin Adults: Genes and Environment (STAGE)

, 2012
Kelly Donahue, Brian M. D’Onofrio, Paul Lichtenstein, Niklas Långström   +3 more
openalex   +2 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Epigenetic Clocks as Biomarkers for Bone Aging: Evidence From a Twin Study. [PDF]

Aging Cell
Soerensen M, Figeac F, Christensen K, Kassem M.   +3 more
europepmc   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

A Study on a Twin System for AMHTS (1st Report)

, 1990
稲田 紘, 石川 澄, 玉井 正彦, 杉本 敞一, 久徳 均, 吉川 博通   +5 more
openalex   +2 more sources

Digital Twins for predictive maintenance: A case study for a flexible IT-architecture

, 2023
Pascal Mrzyk, Johannes Kubacki, Janosch Luttmer, Robin Pluhnau, Arun Nagarajah   +4 more
openalex   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Data from Cancer-Related Reductions in Survival: Extent and Duration Evaluated Using a Large Cohort Study of Twins, 1943–2011

Martin Dalgaard Villumsen, Linda Juel Ahrenfeldt, Kaare Christensen, Marianne Ewertz, Jacob Hjelmborg   +4 more
openalex   +1 more source