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Twin Studies in Genetics

Acta geneticae medicae et gemellologiae, 1972
SummaryAlmost one century after Galton's first scientific formulation of the Twin Method, based on the comparison of MZ and DZ twin series, not only twin studies play a fundamental role and the Interzygotic Test is widely applied in human and especially medical genetic research, but new methods have also been worked out, such as the Azygotic Test and ...
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The validity of twin studies

GeneScreen, 2000
AbstractThe classical twin study is the most popular method for assessing the relative contribution of genes and environment to traits in human populations. Critics argue that several assumptions of the twin method are unjustified, and therefore results from twin studies are misleading. Specifically, it has been suggested that twins differ in important
Evans, D, Martin, NG
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Twin Studies in Pharmacogenetics

1978
Since Galton introduced the twin method in 1875 to study the nature-nurture problem (Galton, 1875), the use of twins to identify the relative contributions of genetic and environmental factors to phenotypic variation among human beings has experienced marked shifts in popularity as a genetic instrument or tool.
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Twin studies in psychotic disorders

Epidemiologia e Psichiatria Sociale, 2009
etiology of major psychoses, particularly schizophrenia and bipolar disorder. Nevertheless, little is known about the nature and extent of the specific genetic contribution to disease liability (Kendler et al., 1993; Danese, 2008). Twin studies can provide crucial insights regarding the etiology of sub-threshold and clinical psychosis, and represent an
BELLANI, Marcella   +2 more
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A Danish Twin Study of Schizophrenia

British Journal of Psychiatry, 1969
Previous studies on schizophrenia in twins have quite recently been reviewed in detail by Gottesman and Shields (1966a) and Shields (1968). The indications of concordance in different series are highly diverging, in monozygotic pairs ranging from near unity to zero.
Fischer, Margit   +2 more
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Studies on Twins IV. Twinning in Madhya Pradesh

Acta geneticae medicae et gemellologiae, 1970
Frequency and inheritance of twinning have been studied from urban and rural parts of Madhya Pradesh. Family data conform to previous findings by other authors, for other countries, that DZ twinning is influenced by the mother's genotype.Of special interest has been a rural family in which a female, herself a cotwin of DZ pair, married twice, each time
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Panic attacks: a twin study

Psychiatry Research, 1997
The role of genetic factors in panic disorder (PD) and sporadic panic attacks (SPAs) was investigated. A total of 120 twins recruited from the general population were interviewed for the presence of anxiety disorders and SPAs. A significantly higher concordance among MZ than DZ twins was found for PD (73% vs. 0%) but not for SPAs (57% vs. 43%).
Perna G   +3 more
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“Macrosomic” Twinning

Obstetrics & Gynecology, 1990
We evaluated 56 twin pregnancies representing the tenth decile of the mean twin birth weight distribution to investigate whether larger twins face the same increased perinatal risk as do macrosomic singletons. Compared with pregnancies in the ninth decile, no significant difference was found between the means of maternal age, parity, and gestational ...
Isaac Blickstein, Ariel Weissman
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The Study of Twin Experience as Twins

2020
The experience of twins as twins is rarely studied. Objectivist science has used identical twins as ideal test subjects because their identical DNA provides an easy control mechanism that is unavailable in singletons. The aim in these studies is to discover fundamental links between genetics, behavior, and personality characteristics.
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Twin-to-Twin Transfusion Syndrome

Advances in Neonatal Care, 2013
Twin-to-twin transfusion syndrome (TTTS) is a disease that affects roughly 15% of monochorionic twins. Although TTTS is not extremely prevalent, the rate of mortality and morbidly approaches 100% without early detection and treatment. The following case study is a triplet pregnancy that included a set of monochorionic twins affected by TTTS. Typically,
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