Results 211 to 220 of about 41,814,406 (368)

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

The metabolic signature of blood lipids: a causal inference study using twins

open access: yesJournal of Lipid Research
Dyslipidemia is one of the cardiometabolic risk factors that influences mortality globally. Unraveling the causality between blood lipids and metabolites and the complex networks connecting lipids, metabolites, and other cardiometabolic traits can help ...
Yutong Wang   +15 more
doaj  

The development of emotional overeating: a longitudinal twin study from toddlerhood to early adolescence. [PDF]

open access: yesInt J Behav Nutr Phys Act
Madhavan VK   +4 more
europepmc   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

open access: yesMolecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren   +4 more
wiley   +1 more source

Prevalence, Concordance, and Heritability of Vitreomacular Interface Abnormalities in a Twin Study. [PDF]

open access: yesInvest Ophthalmol Vis Sci, 2023
Jarrar ZA   +6 more
europepmc   +1 more source

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