Results 231 to 240 of about 41,814,406 (368)

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

Relative contributions of genetic and environmental factors to palatal morphology: a longitudinal twin study. [PDF]

open access: yesEur J Orthod
Giri J   +6 more
europepmc   +1 more source

Aversive and Reinforcing Opioid Effects: A Pharmacogenomic Twin Study

open access: yesAnesthesiology, 2012
M. Angst   +7 more
semanticscholar   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

Generalized domain prompt learning for accessible scientific vision-language models

open access: yesNexus
Large-scale vision-language models have shown remarkable success in general vision tasks, inspiring the development of domain-specific models. However, creating these models requires substantial investments in annotated data, computational resources, and
Qinglong Cao   +6 more
doaj  

VETSA: The Vietnam Era Twin Study of Aging

open access: yesTwin Research and Human Genetics, 2012
W. Kremen, C. Franz, M. Lyons
semanticscholar   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

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