Results 251 to 260 of about 785,061 (339)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Urine metabolomic profiles of autism and autistic traits-A twin study. [PDF]

PLoS One
Arora A, Mastropasqua F, Bölte S, Tammimies K.   +3 more
europepmc   +1 more source

Reanalysis of twin studies suggests that diabetes is mainly genetic.

, 2001
Edwin Gale, Polly J. Bingley, George S. Eisenbarth, María J. Redondo, Kirsten Ohm Kyvik, Jacob Petersen   +5 more
openalex   +1 more source

Genetic and environmental influences on structural brain development from childhood to adolescence: A longitudinal twin study on cortical thickness, surface area, and subcortical volume

Lina van Drunen, Simone Dobbelaar, Eveline A. Crone, Lara M. Wierenga   +3 more
openalex   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Genetic and environmental contributions to the development of dental arch traits: a longitudinal twin study. [PDF]

Eur J Orthod
Giri J, Bockmann M, Brook A, Gurr A, Palmer L, Hughes T.   +5 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Protein epigenetic scores and overall mortality in the longitudinal Swedish Adoption/Twin Study of Aging (SATSA). [PDF]

Clin Epigenetics
Lopes De Oliveira T, March A, Mak JKL, Pedersen NL, Hägg S.   +4 more
europepmc   +1 more source

The impact of camouflaging autistic traits on psychological and physiological stress: a co-twin control study

Sabela Conde-Pumpido Zubizarreta, Johan Isaksson, Åshild Faresjö, Tomas Faresjö, Ángel Carracedo, Montse Fernández‐Prieto, Sven Bölte, Karl Lundin Remnélius   +7 more
openalex   +1 more source