Results 131 to 140 of about 57,012 (243)

Does Education Pay in Urban China? Estimating Returns to Education Using Twins [PDF]

open access: yes
This paper empirically estimates the returns to education using twins data that the authors collected from urban China. Our ordinary least-squares estimate shows that one year of schooling increases an individual¡¦s earnings by 8.4 percent. However, once
Hongbin Li   +3 more
core  

Genome‐Wide 5‐Methylcytosine and 5‐Hydroxymethylcytosine Signatures Analysis of Plasma Cell‐Free DNA in Schizophrenia

open access: yesMedComm, Volume 6, Issue 8, August 2025.
We performed cfDNA 5‐methylcytosine (5mC) and 5‐hydroxymethylcytosine (5hmC) sequencing of plasma samples from 66 individuals with SCZ and 77 healthy controls (HC). We identified differentially 5mC methylated regions (DMRs) and differentially 5hmC hydroxymethylated regions (DhMRs) that showed distinct patterns between SCZ and control samples.
Gang Xue   +13 more
wiley   +1 more source

Multi‐Omic Associations of Epigenetic Age Acceleration Are Heterogeneously Shaped by Genetic and Environmental Influences

open access: yesAging Cell, Volume 24, Issue 8, August 2025.
The connections between epigenetic age acceleration (EAA) and the multi‐ome, as well as the extent to which these connections are driven by genetic and environmental factors, remain underexplored. We identified blood proteins, metabolites, and exposures associated with EAA in young adults and, using twin study designs, show that these associations are ...
Gabin Drouard   +5 more
wiley   +1 more source

Clinical research updates

open access: yes
Child and Adolescent Mental Health, Volume 30, Issue 3, Page 323-324, September 2025.
Marinos Kyriakopoulos   +3 more
wiley   +1 more source

Brain DNA Methylation Age, Lifestyle Factors and Dementia in the Swedish Twin Registry

open access: yesAging Cell, Volume 24, Issue 8, August 2025.
DNA methylation age (DNAmAge) uses molecular information to quantify biological ageing. We assessed brain‐specific DNAmAge among Swedish Twin Registry participants, revealing adverse associations with smoking and protective associations with education. Dementia outcomes were not clearly associated with brain DNAmAge.
Christopher E. McMurran   +6 more
wiley   +1 more source

Identifying Genomic Variations in Monozygotic Twins Discordant for Autism Spectrum Disorder Using Whole-Genome Sequencing

open access: yesMolecular Therapy: Nucleic Acids, 2019
Autism spectrum disorder (ASD) presents a set of childhood neurodevelopmental disorders with impairments in social communication and restricted, repetitive, and stereotyped patterns of behavior.
Yan Huang   +10 more
doaj  

CDK13‐Related Disorder: Novel Insights From A Series of 27 Cases and Recommendations for Clinical Management

open access: yesClinical Genetics, Volume 108, Issue 2, Page 146-155, August 2025.
This report described 27 novel subject with CDK13‐related disorders. Collecting the clinical and radiological data, we better define the phenotypic spectrum of this condition and we suggest a comprehensive clinical management. ABSTRACT In 2016, Sifrim and colleagues described the first group of patients carrying heterozygous pathogenic variants in ...
Gianluca Contrò   +57 more
wiley   +1 more source

Proteomic associations with fluctuation and long‐term changes in BMI: A 40‐year follow‐up study

open access: yesDiabetes, Obesity and Metabolism, Volume 27, Issue 8, Page 4192-4202, August 2025.
Abstract Introduction While some studies have explored associations between weight change and blood proteins, most have been intervention‐based, offering limited insight into proteomic associations with long‐term weight gain. It remains unclear whether plasma proteins are related to BMI fluctuation over time.
Alvaro Obeso   +6 more
wiley   +1 more source

Improvements and Future Challenges in the Field of Genetically Sensitive Sample Designs [PDF]

open access: yes
Understanding the sources of individual differences beyond social and economic effects has become a research area of growing interest in psychology, sociology, and economics.
Frank M. Spinath
core  

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