Results 151 to 160 of about 346,692 (290)

Generation and characterization of human-derived iPSC lines from three pairs of monozygotic twins discordant for Parkinson's disease

open access: yesStem Cell Research, 2019
Despite a genetic component in the development of Parkinson’s disease (PD), monozygotic twin pairs often display discordance for PD. Here, we describe the generation of six human induced pluripotent stem cell (iPSC) lines from dermal fibroblasts of three
Marija Dulovic-Mahlow   +10 more
doaj  

Ovarian Mature and Immature Teratomas in Monozygotic Twins: A Case Report of Simultaneous Presentation

open access: yesCase Reports in Obstetrics and Gynecology, 2017
Mature cystic teratoma is one of the most common kinds of ovarian tumor, and immature teratoma is a rare tumor, representing less than 1% of all ovarian teratomas.
Daisuke Shigemi   +2 more
doaj   +1 more source

Therapeutic drug monitoring, liquid biopsies or pharmacogenomics for prediction of human drug metabolism and response

open access: yesBritish Journal of Clinical Pharmacology, Volume 91, Issue 6, Page 1569-1579, June 2025.
Pharmacokinetics plays a central role in understanding the significant interindividual differences that exist in drug metabolism and response. Effectively addressing these differences requires a multi‐faceted approach that encompasses a variety of tools and methods.
Magnus Ingelman‐Sundberg, Espen Molden
wiley   +1 more source

Strikingly higher frequency in centenarians and twins of mtDNA mutation causing remodeling of replication origin in leukocytes [PDF]

open access: yes, 2003
The presence of a genetic component in longevity is well known. Here, the association of a mtDNA mutation with a prolonged life span in humans was investigated.
Asin-Cayuela, Jordi   +9 more
core  

Pyloric Stenosis in Premature Twins: A Case Report

open access: yes
Journal of Paediatrics and Child Health, EarlyView.
S. P. Y. Tan Tanny   +4 more
wiley   +1 more source

Exploring Behavioural Patterns in Youth Predisposed to Bipolar Disorder and the Role of Interpersonal Trauma Using the Adolescent Brain Cognitive Development (ABCD) Dataset

open access: yesEarly Intervention in Psychiatry, Volume 19, Issue 6, June 2025.
ABSTRACT Introduction Bipolar disorder (BD) is a severe, persistent disorder that causes functional impairment. Besides heritability, environmental factors, such as traumatic experience, impact the development of BD. Little is known about the early developmental signs of this disorder; therefore, this study aims to look at the impact of interpersonal ...
Christina Ghaleb   +3 more
wiley   +1 more source

Class - III malocclusion: Genetics or environment? A twins study

open access: yesJournal of Indian Society of Pedodontics and Preventive Dentistry, 2005
Etiology of class-III malocclusion is generally believed to be genetic. A wide range of environmental factors have been suggested as contributing factors for the development of class-III malocclusion.
Jena A, Duggal R, Mathur V, Parkash H
doaj  

Heritability of children's Secure Base Script Knowledge in middle childhood: a twin study with the Attachment Script Assessment

open access: yesJournal of Child Psychology and Psychiatry, Volume 66, Issue 6, Page 796-804, June 2025.
Background Are individual differences in attachment security inborn or shaped by the social environment? In infancy and early childhood, the evidence points to a substantial role of the environment, but a large twin study in early adolescence showed considerable heritability. Here we examined the twin heritability of attachment in middle childhood.
Jana Runze   +3 more
wiley   +1 more source

Happy is as Happy Does [PDF]

open access: yes, 1997
Although Lykken & Tellegen (1996) have shown that the stable component of happiness or subjective well-being is strongly influenced by genetic factors, One needn't permit one's own or one's child's genetic steersman have his head.
Lykken, David T.
core  

Research Review: A review of the past decade of family and genomic studies on adolescent mental health

open access: yesJournal of Child Psychology and Psychiatry, Volume 66, Issue 6, Page 910-927, June 2025.
Background Mental health problems and traits capturing psychopathology are common and often begin during adolescence. Decades of twin studies indicate that genetic factors explain around 50% of individual differences in adolescent psychopathology.
Geneviève Morneau‐Vaillancourt   +3 more
wiley   +1 more source

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