Results 31 to 40 of about 31,362 (252)

Copy number variation analysis of twin pairs discordant for cleft lip with or without cleft palate

International Journal of Immunopathology and Pharmacology, 2019
Non-syndromic cleft lip with or without cleft palate (nsCL/P) is a frequent orofacial malformation. The comparison of concordance rate observed in monozygotic and dizygotic twins supports high level of heritability and a strong genetic component. However,
Luca Scapoli, Francesco Carinci, Annalisa Palmieri, Francesca Cura, Alessandro Baj, Giada Beltramini, Raffaella Docimo, Marcella Martinelli   +7 more
doaj   +1 more source

Genetic, environmental and stochastic factors in monozygotic twin discordance with a focus on epigenetic differences

, 2012
Genetic-epidemiological studies on monozygotic (MZ) twins have been used for decades to tease out the relative contributions of genes and the environment to a trait.
Morahan, JM, Ramagopalan, SV, Ebers George C, Czyz Witold, Ramagopalan, Sreeram, George C Ebers, Sreeram V Ramagopalan, Ebers, GC, Ramagopalan Sreeram V, Witold Czyz, Julia M Morahan, Morahan Julia M, Ebers, George, Czyz, W   +13 more
core   +1 more source

Discordant renal progression of Fabry disease in male monozygotic twins: a case report

Frontiers in Genetics, 2023
Background: Fabry disease (FD) is a rare X-linked lysosomal storage disease caused by mutations in the GLA gene that encodes α-galactosidase A (α-GAL).
Do-Yun Lee, Jun-Yeong Jeong, Seung-Eun Lee, Jae-Hun Lee, Ju-Young Moon, Su Woong Jung, Sang-Ho Lee, Yang Gyun Kim   +7 more
doaj   +1 more source

Equivalent DNA methylation variation between monozygotic co-twins and unrelated individuals reveals universal epigenetic inter-individual dissimilarity

Genome Biology, 2021
Background Although the genomes of monozygotic twins are practically identical, their methylomes may evolve divergently throughout their lifetime as a consequence of factors such as the environment or aging. Particularly for young and healthy monozygotic
Benjamin Planterose Jiménez, Fan Liu, Amke Caliebe, Diego Montiel González, Jordana T. Bell, Manfred Kayser, Athina Vidaki   +6 more
doaj   +1 more source

A Twin Study of Genetic Contributions to Hippocampal Morphology in Schizophrenia

Neurobiology of Disease, 2002
Our goal was to establish whether altered hippocampal morphology represents a trait marker for genetic vulnerability in schizophrenia. We outlined the hippocampi on high-resolution MR images obtained from matched samples of control and discordant ...
Katherine L. Narr, Theo G.M. van Erp, Tyrone D. Cannon, Roger P. Woods, Paul M. Thompson, Seonah Jang, Rebecca Blanton, Veli-Pekka Poutanen, Matti Huttunen, Jouko Lönnqvist, Carl-Gustav Standerksjöld-Nordenstam, Jaakko Kaprio, John C. Mazziotta, Arthur W. Toga   +13 more
doaj   +1 more source

Indian twin registry: A gold mine for genetic studies

Asian Journal of Medical Sciences, 2023
Twins are a source of curiosity, both for the family and the scientific community. Genetic similarities between twins have been the preferred choice to study the heritability of traits.
Ruby Dhar , Arun Kumar , Subhradip Karmakar   +2 more
doaj   +1 more source

“Identical” double parathyroid adenomas in monozygotic twins

Otolaryngology Case Reports, 2021
A number of genes have been associated with sporadic causes of primary hyperparathyroidism. A case of primary hyperparathyroidism secondary to simultaneously presenting double parathyroid adenomas with identical distribution in a set of 48-year-old ...
F. Jeffrey Lorenz
doaj   +1 more source

Neurometabolic Stability and Heritability in the Adolescent Brain: A Preliminary Longitudinal Twin MRS Study. [PDF]

NMR Biomed
In this preliminary longitudinal MRS study of early adolescent twins, neurometabolite ratios in the prefrontal cortex and thalamus appeared relatively stable over a 6‐month interval. Moderate heritability estimates were observed for prefrontal Glx (glutamine + glutamate) as well as thalamic glutamate and choline compounds, suggesting possible region ...
Hamann C, Markovic A, Caccia J, Badek A, Wild S, Adorjan K, Kaess M, Tuura R, Tarokh L.   +8 more
europepmc   +2 more sources

The relationship between Hippocampal asymmetry and working memory processing in combat-related PTSD: a monozygotic twin study

, 2012
BACKGROUND: PTSD is associated with reduction in hippocampal volume and abnormalities in hippocampal function. Hippocampal asymmetry has received less attention, but potentially could indicate lateralised differences in vulnerability to trauma.
McFarlane, Alexander, Veltmeyer, Melinda, Hall, T., Metzger, L., Melinda Veltmeyer, Gilbertson, Mark, Orr, Scott, Gilbertson, M., Linda J Metzger, Galletly, C., Roger K Pitman, Pitman, Roger, Cherrie Galletly, Clark, C Richard, Veltmeyer, M., Orr, S., Clark, C., Alexander McFarlane, McFarlane, A., C Clark, Pitman, R., Timothy Hall, Hall, Timothy, Scott P Orr, Metzger, Linda J, Mark W Gilbertson, Galletly, Cherrie   +26 more
core   +1 more source

Monozygotic twins discordant for low-level mosaic trisomy 17 at amniocentesis in a pregnancy with a favorable outcome and a literature review of heterokaryotypic monozygotic twins at amniocentesis

Taiwanese Journal of Obstetrics & Gynecology, 2020
Objective: We present a set of twins discordant for low-level mosaic trisomy 17 at amniocentesis, and we review the literature of heterokaryotypic monozygotic twins at amniocentesis.
Chih-Ping Chen, Schu-Rern Chern, Peih-Shan Wu, Shin-Wen Chen, Shih-Ting Lai, Fang-Tzu Wu, Dai-Dyi Town, Wayseen Wang   +7 more
doaj   +1 more source