Results 61 to 70 of about 59,137 (242)

Subclinical hypomania, psychiatric and neurodevelopmental diagnoses: phenotypic and aetiological overlap

Journal of Child Psychology and Psychiatry, EarlyView.
Background Subclinical hypomanic symptoms are fairly common in the general population but are linked to psychiatric and neurodevelopmental conditions. However, the genetic and environmental origins of these associations are unclear. This twin study examined the phenotypic and aetiological associations between subclinical hypomania and psychiatric and ...
Georgina M. Hosang, Miriam I. Martini, Angelica Ronald, Henrik Larsson, Sebastian Lundström, Paul Lichtenstein, Mark J. Taylor   +6 more
wiley   +1 more source

Trigger Twins: 2 Cases of Ipsilateral Twin Trigger Digit and a Review of Published Literature

Case Reports in Orthopedics, 2019
Background. The aetiology of trigger digits has been debated since Notta first described them in 1850. Aetiology has been segregated for adult and paediatric presentations. While an adult trigger digit is most likely an acquired inflammatory process, the
David Brinkman, Gerard Sheridan, Michael O’Sullivan   +2 more
doaj   +1 more source

Increased expression and altered methylation of HERVWE1 in the human placentas of smaller fetuses from monozygotic, dichorionic, discordant twins. [PDF]

PLoS ONE, 2012
BACKGROUND: The human endogenous retroviral family W, Env(C7), member 1 gene (HERVWE1) is thought to participate in trophoblast cell fusion, and its expression is diminished in the placentas of singleton intrauterine growth-retarded pregnancies. However,
Yu Gao, Zhiming He, Zilian Wang, Yanmin Luo, Hongyu Sun, Yi Zhou, Linhuan Huang, Manchao Li, Qun Fang, Shiwen Jiang   +9 more
doaj   +1 more source

A placebo-controlled trial of folic acid and betaine in identical twins with Angelman syndrome. [PDF]

, 2019
BackgroundAngelman syndrome (AS) is a neurodevelopmental disorder that is caused by maternal genetic deficiency of a gene that encodes E6-AP ubiquitin-protein ligase (gene symbol UBE3A) mapping to chromosome 15q11-q13.
Anselm, Irina, Bacino, Carlos A, Bichell, Terry Jo, Bird, Lynne M, Golden, Stephanie, Han, Julia, Kimonis, Virginia, Peters, Sarika U, Waisbren, Susan   +8 more
core  

A person‐centered and genetically informed approach toward characterizing multidomain resilience to neighborhood disadvantage in youth

Journal of Child Psychology and Psychiatry, EarlyView.
Background Examining resilience to adversity across multiple behavioral domains (e.g., psychological well‐being, social functioning) can better characterize positive development and inform novel prevention and intervention efforts. However, few studies have employed person‐centered methods to examine individual profiles of resilience across multiple ...
Jessica L. Bezek, Elizabeth A. Shewark, Gabriela L. Suarez, Kelly L. Klump, S. Alexandra Burt, Luke W. Hyde   +5 more
wiley   +1 more source

Serum lipids and serum uric acid in human twins

Journal of Lipid Research, 1965
This report describes a study of serum total cholesterol, free cholesterol, glyceride glycerol, total phospholipids, and uric acid in human twins and is presented in three sections.Section 1 presents evidence that interpair variance of free cholesterol ...
Julius Jensen, David H. Blankenhorn, H.P. Chin, Phillip Sturgeon, Arnold G. Ware   +4 more
doaj   +1 more source

The Gut Microbiota Composition in Dichorionic Triplet Sets Suggests a Role for Host Genetic Factors [PDF]

, 2015
peer-reviewedMonozygotic and dizygotic twin studies investigating the relative roles of host genetics and environmental factors in shaping gut microbiota composition have produced conflicting results.
Dempsey, Eugene, Murphy, Kiera, O'Shea, Carol A, O'Toole, Paul W., Ross, R Paul, Ryan, C. Anthony, STANTON, CATHERINE   +6 more
core   +2 more sources

Neurodevelopmental conditions and adaptive functioning – a co‐twin control study

Journal of Child Psychology and Psychiatry, EarlyView.
Background Challenges in adaptive or daily functioning are inherent to diagnostic criteria for neurodevelopmental conditions (NDCs). However, less is known regarding the influence of factors that may confound the association between NDCs and adaptive functioning.
Johan Isaksson, Filippa Eklund, Karl Lundin Remnélius, Melissa H. Black, Sven Bölte   +4 more
wiley   +1 more source

Whole genome and exome sequencing of monozygotic twins with trisomy 21, discordant for a congenital heart defect and epilepsy. [PDF]

PLoS ONE, 2014
Congenital heart defects (CHD) occur in 40% of patients with trisomy 21, while the other 60% have a structurally normal heart. This suggests that the increased dosage of genes on chromosome 21 is a risk factor for abnormal heart development.
Pongsathorn Chaiyasap, Supasak Kulawonganunchai, Chalurmpon Srichomthong, Sissades Tongsima, Kanya Suphapeetiporn, Vorasuk Shotelersuk   +5 more
doaj   +1 more source

The nature and nurture of primary and secondary callous–unemotional traits: evidence from two independent twin samples

Journal of Child Psychology and Psychiatry, EarlyView.
Background Callous–unemotional (CU) traits identify youth with more severe and chronic trajectories of conduct problems. However, the etiology of CU traits may be heterogeneous, undermining the search for effective treatments. The level of co‐occurring anxiety has been used to identify “primary” (lower anxiety) versus “secondary” (higher anxiety ...
Rachel C. Tomlinson, Patrizia Pezzoli, Essi Viding, Stephane A. De Brito, Kelly L. Klump, S. Alexandra Burt, Luke W. Hyde   +6 more
wiley   +1 more source