Results 291 to 300 of about 524,795 (331)

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

open access: yesFEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Genetic diversity and population structure of the Taigan dog breed

open access: yesFEBS Open Bio, EarlyView.
The Taigan is a rare sighthound from the mountains of Kyrgyzstan. We used DNA markers to study its genetic diversity and compare it with other sighthound breeds. Our findings show that the Taigan shares close genetic ties with the Kazakh Tazy, suggesting a common ancestry shaped by nomadic traditions and regional adaptation.
Kira Bespalova   +10 more
wiley   +1 more source

Genetic and Environmental Effects on Parent-Rated Adaptive Behaviour in Infancy. [PDF]

open access: yesDev Sci
Halkola H   +5 more
europepmc   +1 more source

Digital twin manifesto for the pathology laboratory. [PDF]

open access: yesDiagn Pathol
Eccher A   +9 more
europepmc   +1 more source

Digital twins, synthetic patient data, and in-silico trials: can they empower paediatric clinical trials? [PDF]

open access: yesLancet Digit Health
Pammi M   +5 more
europepmc   +1 more source

Source-tracking Klebsiella outbreaks in premature infants using a novel amplicon fingerprinting method. [PDF]

open access: yesAntimicrob Resist Infect Control
Matson AP   +7 more
europepmc   +1 more source

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