Results 41 to 50 of about 94,633 (199)

Intravenous mesenchymal stem cell transplantation mitigates pulmonary vascular remodeling but poses dose related risks in a pulmonary veno-occlusive disease model

Stem Cell Research & Therapy
Background Pulmonary veno-occlusive disease (PVOD) is a rare subtype of disease that causes pulmonary hypertension with vascular involvement of postcapillary structures of pulmonary vasculature. The disease has a poor prognosis with no effective therapy.
Junko Katagiri, Jun Homma, Ryo Takagi, Hidekazu Sekine, Takeshi Shinkawa, Hiroshi Niinami, Tatsuya Shimizu   +6 more
doaj   +1 more source

Xenogeneic transplantation of human adipose-derived stem cell sheets accelerate angiogenesis and the healing of skin wounds in a Zucker Diabetic Fatty rat model of obese diabetes

Regenerative Therapy, 2017
Introduction: Diabetic patients with foot ulcers often suffer impaired wound healing due to diabetic neuropathy and blood flow disturbances. Direct injection of human adipose-derived stem cells (hASCs) effectively accelerates wound healing, although ...
Mariko Hamada, Takanori Iwata, Yuka Kato, Kaoru Washio, Shunichi Morikawa, Hiroyuki Sakurai, Masayuki Yamato, Teruo Okano, Yasuko Uchigata   +8 more
doaj   +1 more source

Prevalence and Spectrum of Congenital Anomalies in Multiple Births with Analysis of Demographic and Obstetric Risk Factors [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Recently, there is an increase in incidence of Congenital Anomalies (CA) more so in case of multiple births. But literature regarding the prevalence of congenital anomalies in combination with multiple births, the association of maternal ...
Asaranti Kar, Sony Nanda, Tushar Kar, Ipsita Dhal, Bidyut Prabha Satpathy, Kirtirekha Mohapatra   +5 more
doaj   +1 more source

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm, Imme Haubitz, Rita Beier, Martin Zimmermann, Andrej Lissat, Peter Bader, Matthias Eyrich, Jan‐Henning Klusmann, Matthias Wölfl, Paul‐Gerhardt Schlegel, Verena Wiegering   +10 more
wiley   +1 more source

Chondrocyte Differentiation of Human Endometrial Gland-Derived MSCs in Layered Cell Sheets

The Scientific World Journal, 2013
Recently, regenerative medicine using engineered three-dimensional (3D) tissues has been focused. In the fields of cell therapy and regenerative medicine, mesenchymal stem cells (MSCs) are attractive autologous cell sources.
Waki Sekine, Yuji Haraguchi, Tatsuya Shimizu, Masayuki Yamato, Akihiro Umezawa, Teruo Okano   +5 more
doaj   +1 more source

First trimester prenatal screening in multiple pregnancies. Part II: serum proteins PAPP-A and β-hCG as markers of adverse pregnancy outcomes

Акушерство, гинекология и репродукция, 2020
Aim: to evaluate the ability of serum biochemical markers in pregnant woman - PAPP-A (pregnancy-associated plasma protein-A) and β-hCG (the в-subunit of human chorionic gonadotropin) studied in the first trimester (11+0-13+6) during combined prenatal ...
V. I. Tsibizova, I. E. Govorov, T. M. Pervunina, E. V. Komlichenko, E. K. Kudryashova, D. V. Blinov, A. D. Makatsariya, G. C. Di Renzo   +7 more
doaj   +1 more source

Evaluation of the Utility of Baseline Echocardiogram in Patients With Standard Risk Precursor B‐Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
Abstract Background A routine baseline echocardiogram is often obtained prior to anthracycline administration in children with cancer. The utility of baseline echocardiogram is unclear in patients with standard risk B‐cell acute lymphoblastic leukemia (SR B‐ALL) as their anthracycline cumulative dose is low.
Ziyad Alrajhi, Alice Pozza, Luc Mertens, Adam Paul Yan, Sarah Alexander   +4 more
wiley   +1 more source

Crop cultivation without nitrogen fertiliser using nitrogen-fixing cyanobacterial extracts for low environmental impact

Scientific Reports
In this study, we attempted to develop a biological fertiliser using the nitrogen-fixing cyanobacterium, Trichormus sp. PCC7120, with the aim of constructing a sustainable farming method for growing crops without chemical fertilisers.
Yuji Haraguchi, Tatsuya Shimizu
doaj   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source