Results 51 to 60 of about 524,795 (331)
Twins in Mesoamerica as a Symbol of Contrasting Duality [PDF]
, 2015 In cultures across the Mesoamerican subcontinent, there are examples in the archaeological and ethnographic record of myths concerned with twins and sibling pairs (Minneci, 1999).
Rideout, Benjamin
core +2 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Low-adhesion culture selection for human iPS cell-derived cardiomyocytes
Scientific ReportsDespite progress in generating cardiomyocytes from pluripotent stem cells, these populations often include non-contractile cells, necessitating cardiomyocyte selection for experimental purpose.
Tetsutaro Kikuchi +2 more
doaj +1 more source
Frontiers in Public Health, 2022 BackgroundYoung children in Sub-Saharan Africa (SSA), particularly those from resource-limited settings, are heavily burdened by anemia and malaria. While malaria infected children frequently become anemic (hemoglobin < 110 g/L), anemia is a strongly ...
Tim Starck +18 more
doaj +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Metagenomic Analysis of the Structure and Function of the Human Gut Microbiota in Crohn's Disease [PDF]
, 2010 Inflammatory bowel diseases (IBD), such as Crohn’s disease, are chronic, immunologically mediated disorders that have severe medical consequences.
Claire M. Fraser-Liggett
core +2 more sources
Physiological ReportsCardiac alternans (C‐ALT) is a phenomenon of alternating strong and weak contractions in the heart and is considered a risk factor for the development of heart failure and arrhythmias.
Yuto Hinata +3 more
doaj +1 more source
Energy Reports, 2022 Existing grids have been designed with traditional large centralized generation in mind; however, with the ever-increasing utilization of renewable distributed energy resources, the challenges of proper grid management have intensified.
Freddy Plaum +3 more
doaj
Biology Open, 2013 Summary The African clawed frog, Xenopus laevis, is an ectothermic vertebrate that can survive at low environmental temperatures. To gain insight into the molecular events induced by low body temperature, liver proteins were evaluated at the standard ...
Kazumichi Nagasawa +5 more
doaj +1 more source