Results 271 to 280 of about 2,123,405 (317)
Some of the next articles are maybe not open access.
Phase diagrams: two-component systems
2013Contents Liquid–vapour systems 664 Pressure–composition diagrams 664 Brief illustration 68.1: The lever rule 665 Temperature–composition diagrams 665 Brief illustration 68.2: Azeotropes ...
Peter Atkins +2 more
openaire +1 more source
The rotating rodent: A two component system?
European Journal of Pharmacology, 1978The hypothesis that the rotating rat requires both nigro-striatal and mesolimbic dopaminergic components for activity has been tested. 6-Hydroxydopamine lesions were induced unilaterally in either or both the ascending nigrostriatal and mesolimbic dopamine pathway. In one group of rats the nucleus accumbens was destroyed bilaterally with electrolesions.
C J, Pycock, C D, Marsden
openaire +2 more sources
Inhibitors of bacterial two-component signalling systems
Expert Opinion on Investigational Drugs, 2000Bacterial two-component regulatory systems (TCS) play a pivotal role in the process of infection. These signal transduction systems enable bacterial pathogens to mount an adaptive response and cope with diverse environmental stresses, including nutrient deprivation, antibiotic onslaught and phagocytosis.
M J, Macielag, R, Goldschmidt
openaire +2 more sources
Signalling pathways in two-component phosphorelay systems
Trends in Microbiology, 1999Two-component systems are characterized by phosphotransfer reactions involving histidine and aspartate residues in highly conserved signalling domains. Although the basic principles of signal transduction by these systems have been elucidated, several important aspects, such as their integration into more complex cellular regulatory networks and the ...
A L, Perraud, V, Weiss, R, Gross
openaire +2 more sources
The FMN-dependent two-component monooxygenase systems
Archives of Biochemistry and Biophysics, 2010The FMN-dependent two-component monooxygenase systems catalyze a diverse range of reactions. These two-component systems are composed of an FMN reductase enzyme and a monooxygenase enzyme that catalyze the oxidation of various substrates. The role of the reductase is to supply reduced flavin to the monooxygenase enzyme, while the monooxygenase enzyme ...
openaire +2 more sources
Vancomycin Resistance VanS/VanR Two-Component Systems
2008Vancomycin is a member of the glycopeptide class of antibiotics. Vancomycin resistance (van) gene clusters are found in human pathogens such as Enterococcus faecalis, Enterococcus faecium and Staphylococcus aureus, glycopeptide-producing actinomycetes such as Amycolotopsis orientalis, Actinoplanes teichomyceticus and Streptomyces toyocaensis and the ...
Hee-Jeon, Hong +2 more
openaire +2 more sources
Evolutionary Characteristics of Bacterial Two-Component Systems
2012The evolution of biological systems is influenced by a number of factors and forces that have acted in different combinations at different times to give rise to extant organisms. Here we illustrate some of the issues surrounding the data-driven evolutionary analysis of biological systems in the context of bacterial two-component systems (TCSs).
Xia, Sheng +3 more
openaire +2 more sources
Plant Covirus Systems: Two-Component Systems
1977The central concept concerning the viruses described in this chapter is that they have in common the following characteristic: the minimum genetic entity which can be derived from the virus, and which can induce an infection in which virions are formed, is two pieces of RNA.
openaire +1 more source
Small RNAs Controlled by Two-Component Systems
2008Two-component systems (TCSs) allow bacteria to monitor diverse environmental cues and to adjust gene expression accordingly at the transcriptional level. It has been recently recognized that prokaryotes also regulate many genes and operons at a posttranscriptional level with the participation of small, noncoding RNAs which serve to control translation ...
Claudio, Valverde, Dieter, Haas
openaire +2 more sources
Bacterial Two-Component Regulatory Systems
1998Two-component regulation involves a stimulus-sensitive sensor (histidine protein kinase) that controls the phosphorylation state, and therefore the activity, of its cognate response regulator. Specific two-component systems regulate bacterial response to a wide range of environmental conditions, and many variations on the basic theme have been ...
openaire +1 more source