Results 41 to 50 of about 15,180,548 (316)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

An analytical, phenomenological and numerical study of geophysical and magnetohydrodynamic turbulence in two dimensions [PDF]

open access: yes, 2013
In this thesis I study a variety of two-dimensional turbulent systems using a mixed analytical, phenomenological and numerical approach. The systems under consideration are governed by the two-dimensional Navier-Stokes (2DNS), surface quasigeostrophic
Blackbourn, Luke A. K.
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Two Dimensional-IP Routing [PDF]

open access: yesJournal of Communications, 2013
Traditional IP networks use single-path routing, and make forwarding decisions based on destination address. Source address has always been ignored during routing. Lost of source address makes the traditional routing system inflexible and inefficient. The current network can not satisfy demands of both the network users and the ISP operators.
Mingwei Xu 0001   +3 more
openaire   +1 more source

4th Annual Two-Spirit Pow Wow, San Francisco [PDF]

open access: yes, 2015
Color photograph from the 4th annual Two-Spirit Pow wow, far left in blue shirt Jay Armajo, holding United States Flag David Romero, eagle feather headdress and buckskin regalia Clide Hall, holding staff Liz Gamboa, possibly Lain in dark blue regalia ...
Bay Area American Indian Two Spirits
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Layer-dependent Schottky contact at van der Waals interfaces: V-doped WSe2 on graphene

open access: yesnpj 2D Materials and Applications, 2022
Contacting two-dimensional (2D) semiconductors with van der Waals semimetals significantly reduces the contact resistance and Fermi level pinning due to defect-free interfaces. However, depending on the band alignment, a Schottky barrier remains. Here we
Samuel Stolz   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

2D metallic vanadium dichalcogenides and related heterostructures

open access: yesMaterials Today Advances
Two-dimensional (2D) metallic transition metal dichalcogenides (TMDs) have garnered significant attention as promising candidates for various applications, including electronics, spintronics, and energy-related fields.
Mongur Hossain   +6 more
doaj   +1 more source

Computational studies of one and two-dimensional photonic microstructures [PDF]

open access: yes, 2006
This work is concerned with the study of photonic crystals and other topical photonic microstructures, whose optical properties are investigated by solving the Maxwell equations using appropriate theoretical and computational schemes, which are described.
Beggs, Daryl M., Beggs, Daryl M
core  

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