Results 241 to 250 of about 1,537,923 (347)

In silico predictions of action potential propagation in doxorubicin cardiotoxicity: A parametric study using preclinical 3D magnetic resonance imaging‐based fibrotic left ventricle models

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the study's methodology and key findings. In a preclinical swine model, doxorubicin administration induced cardiotoxicity, characterized by diffuse fibrotic remodelling and altered electrical function, as assessed by magnetic resonance (MR) imaging and electrophysiological mapping.
Javier Villar‐Valero   +7 more
wiley   +1 more source

Determinants of maximal oxygen uptake in highly trained females and males: a mechanistic study of sex differences using advanced invasive methods

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The results from this study show that maximal cardiac output, stroke volume and leg blood flow are similar between highly trained females and males after normalisation to lean body mass (LBM). However, the 10% higher haemoglobin concentration ([Hb]) and arterial O2 content in males result in higher systemic and leg O2 delivery ...
Øyvind Skattebo   +11 more
wiley   +1 more source

4D ultrasound reveals regional left atrial strain remodelling in a murine model of reversible pressure overload

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Traditional planar imaging approaches of the left atrium do not capture complex geometry. Four‐dimensional imaging allows the acquisition of 3D data + time to visualize left atrial geometry and kinematics. We designed an advanced analysis technique to investigate left atrial biomechanics in a model of pressure overload and ...
John P. Salvas   +3 more
wiley   +1 more source

Long‐term passive heat acclimation enhances maximal oxygen consumption via haematological and cardiac adaptation in endurance runners

open access: yesThe Journal of Physiology, EarlyView.
Abstract Figure Legend Endurance‐trained runners completed a 5‐week hot‐water‐immersion (HWI) intervention (≥40°C, 45 min, five sessions per week) and a training‐matched control period in a cross‐over design. HWI induced a 33 g increase in haemoglobin mass (Hbmass) and a 10 mL expansion in left‐ventricular end‐diastolic volume (LVEDV), resulting in a 2.
Elliott J. Jenkins   +7 more
wiley   +1 more source

Free‐Breathing, 3D Cardiac Magnetic Resonance Elastography for Myocardial Stiffness Mapping

open access: yesMagnetic Resonance in Medicine, Volume 95, Issue 4, Page 2356-2369, April 2026.
ABSTRACT Purpose Magnetic resonance elastography (MRE) of the heart has predominantly utilized breath‐held acquisitions with limited anatomic coverage. This work investigates the feasibility of 3D, free‐breathing cardiac MRE. Methods A 3D hybrid radial and EPI acquisition is utilized and combined with retrospective binning of k‐space via physiologic ...
Nolan K. Meyer   +14 more
wiley   +1 more source

The Impact of High‐Intensity Exercise in Normobaric Hypoxia on Right Ventricular Function in Trained and Untrained Men—An Echocardiographic Study

open access: yesComprehensive Physiology, Volume 16, Issue 1, February 2026.
A single bout of high‐intensity exercise to volitional exhaustion under acute normobaric hypoxia (~3000 m a.s.l.; FiO2 = 14.4%) does not induce greater alterations in right ventricular systolic function compared to normoxia in either trained or untrained healthy men.
Gajda Robert   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy