Results 41 to 50 of about 20,728,654 (298)
Патология кровообращения и кардиохирургия, 2015 An atrial septal defect is the most common congenital heart disease. Transcatheter defect closure has become widespread in recent times and the requirements for this procedure are rather strict.
Д. Г. Тарасов +2 more
doaj +1 more source
Transthoracic three-dimensional echocardiography for the assessment of straddling tricuspid or mitral valves [PDF]
, 2000 Background The advent of 3D echocardiography has provided a technique which, potentially, could afford significant additional information over conventional cross-sectional echocardiography in the assessment of patients with straddling atrioventricular ...
Anderson, RH +3 more
core
A Micropeptide Component of the OGDH Complex Modulates ATP Production in the TCA Cycle
Advanced Science, EarlyView.This study identified a mitochondrial micropeptide encoded by a non‐canonical open reading frame (alt‐ORF) within the CTSB gene. This micropeptide named APPM (ATP production‐promoting micropeptide) is a novel component of the OGDHc complex in the TCA cycle. APPM localizes to the inner mitochondrial membrane and directly binds to OGDH, the E1 subunit of
Xinqiang Yin +9 more
wiley +1 more source
Three-dimensional trans-esophageal echocardiographic evaluation of atrial Septal defects : a pictorial essay [PDF]
, 2011 This pictorial assay illustrates the methodology of evaluating the atrial septal defects by three dimensional transesophageal echocardiography with the help of representative images.
Shrivastava, Sameer +2 more
core
Advanced Science, EarlyView.SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang +9 more
wiley +1 more source
EVALUATION OF PATENT DUCTUS ARTERIOSUS BY USING TWO DIMENSIONAL ECHOCARDIOGRAPHY IN INFANT AND NEONATE [PDF]
Zagazig University Medical Journal, 2019 Background: Patent ductus arteriosus (PDA) is a part of the typical morbidity profile of the preterm infant, with a high incidence of 80–90% in extremely low birth weight infants born before 26 weeks of gestation.
Shimaa Mohamed Kamal +2 more
doaj +1 more source
Conventional two-dimensional echocardiography parameters in the investigated groups.
, 2018 Conventional two-dimensional echocardiography parameters in the investigated groups.
Milena Pavlovic Kleut (5435699) +3 more
core +1 more source
An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2
Advanced Science, EarlyView.Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu +7 more
wiley +1 more source
Diagnostics, 2020 Background: Mucopolysaccharidoses (MPSs) are a group of rare inherited metabolic disorders that can damage various organs, including the heart.
Hsiang-Yu Lin +10 more
doaj +1 more source
The Deubiquitinase UCHL1 Drives Susceptibility to Atrial Fibrillation by Stabilizing CaMKII‐δ
Advanced Science, EarlyView.UCHL1 is highly upregulated in mice and patients with AF. UCHL1 directly binds to and removes K48‐linked polyubiquitin chains from CaMKII‐δ at K251 and enhances CaMKII‐δ stability, which activates RyR2, disrupts Ca2+ handling, and promotes AF. These findings establish UCHL1 as a critical regulator of CaMKII‐δ stability and AF‐related Ca2+ handling ...
Hai‐Lian Bi +6 more
wiley +1 more source