Results 61 to 70 of about 29,167,028 (277)

Bipolar carbon and hydrogen isotope constraints on the Holocene methane budget [PDF]

Biogeosciences, 2018
Atmospheric methane concentration shows a well-known decrease over the first half of the Holocene following the Northern Hemisphere summer insolation before it started to increase again to preindustrial values.
J. Beck, J. Beck, M. Bock, M. Bock, J. Schmitt, J. Schmitt, B. Seth, B. Seth, T. Blunier, H. Fischer, H. Fischer   +10 more
doaj   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Bayesian evaluation of the southern hemisphere radiocarbon offset during the holocene [PDF]

, 2009
While an interhemispheric offset in atmospheric radiocarbon levels from AD 1950–950 is now well established, its existence earlier in the Holocene is less clear, with some studies reporting globally uniform 14C levels while others finding Southern ...
Turney, Chris S.M., Palmer, Jonathan G., Ramsey, Christopher Bronk, Turney, Chris, Hogg, Alan, Hogg, Alan G., Palmer, Jonathan, Bronk Ramsey, Christopher, Turney, Chris; id_orcid   +8 more
core   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

A network-based detection scheme for the jet stream core [PDF]

Earth System Dynamics, 2017
The polar and subtropical jet streams are strong upper-level winds with a crucial influence on weather throughout the Northern Hemisphere midlatitudes.
S. Molnos, T. Mamdouh, S. Petri, T. Nocke, T. Weinkauf, D. Coumou   +5 more
doaj   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Magnetic interconnection of Saturn's polar regions: comparison of modelling results with Hubble Space Telescope UV auroral images [PDF]

Annales Geophysicae, 2013
We consider the magnetic interconnection of Saturn's northern and southern polar regions controlled by the interplanetary magnetic field (IMF), studying in particular the more complex and interesting case of southward IMF, when the Kronian ...
E. S. Belenkaya, S. W. H. Cowley, V. V. Kalegaev, O. G. Barinov, W. O. Barinova   +4 more
doaj   +1 more source

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie, Xiaotong Li, Venkata Sita Priyanka Illapani, Leigh N. Sepeta, Jason Schroeder, Chima O. Oluigbo, Madison M. Berl, William D. Gaillard, Nathan T. Cohen   +8 more
wiley   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source

Impact of solar‐induced stratospheric ozone decline on Southern Hemisphere westerlies during the Late Maunder Minimum

Geophysical Research Letters, 2012
The Southern Hemisphere Westerly Winds (SWW) constitute an important zonal circulation system that dominates the dynamics of the Southern Hemisphere mid‐latitudes.
V. Varma, M. Prange, T. Spangehl, F. Lamy, U. Cubasch, M. Schulz   +5 more
doaj   +1 more source