Results 151 to 160 of about 9,407 (294)

Overview of high performance aircraft propulsion research [PDF]

The overall scope of the NASA Lewis High Performance Aircraft Propulsion Research Program is presented. High performance fighter aircraft of interest include supersonic flights with such capabilities as short take off and vertical landing (STOVL) and/or ...
Biesiadny, Thomas J.
core   +1 more source

Decoding the Cardiac Immune Microenvironment and Fibroblast Crosstalk in Radiotherapy Combined with Immunotherapy‐Induced Cardiac Fibrosis Based on Single‐Cell Transcriptomic Analysis

Advanced Science, EarlyView.
This study highlights that radioimmunotherapy drives crosstalk between fibroblasts and immune cells (especially macrophages) in the cardiac microenvironment, with IL‐6 as the key mediator, and tocilizumab alleviates cardiac fibrosis by targeting this interplay.
Yuxi Luo, Ying Yu, Zhimin Zeng, Yanxin Chen, Yali Yi, Zhiqin Lu, Fujuan Zeng, Peng Xu, Daya Luo, Leifeng Chen, Anwen Liu   +10 more
wiley   +1 more source

Flight effects on the aerodynamic and acoustic characteristics of inverted profile coannular nozzles [PDF]

The effect of forward flight on the jet noise of coannular exhaust nozzles, suitable for Variable Stream Control Engines (VSCE), was investigated in a series of wind tunnel tests.
Kozlowski, H., Packman, A. B.
core   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

EDTA‐Functionalized Nanoscale Metal–Organic Framework for Onco‐Cardiology via Radiochemotherapy Synergy and Spatiotemporally Matched Iron Chelation

Advanced Science, EarlyView.
Doxorubicin (DOX)‐induced cardiotoxicity is a major limitation to its broader clinical application, while cardioprotective interventions often risk reducing the anticancer efficacy of DOX. To address these challenges, this work constructs an EDTA‐functionalized metal–organic framework that enhances tumor therapy and provides efficient cardioprotection ...
Daojing Yuan, Liyang Tian, Luwen Zhuang, Yongyu Liang, Lingfei Chen, Xuetao Wang, Yanli Li, Xiyong Yu, Teng Gong   +8 more
wiley   +1 more source

An engine trade study for a supersonic STOVL fighter-attack aircraft, volume 1 [PDF]

The best main engine for an advanced STOVL aircraft flight demonstrator was studied. The STOVL aircraft uses ejectors powered by engine bypass flow together with vectored core exhaust to achieve vertical thrust capability.
Beard, B. B., Foley, W. H.
core   +1 more source

Performance Model Of Co2 Two-Phase Ejector For Subcritical Conditions

, 2016
Carbon dioxide is high pressure fluid. Therefore difference between condensation and evaporation pressures is very high which involves large throttling loss in expansion device. This aspect causes low efficiency of these systems in comparison with conventional compression systems operating with most of synthetic or natural refrigerants.
Smierciew, Kamil, Butrymowicz, Dariusz, Baj, Piotr   +2 more
openaire   +1 more source

Atomic Defects in Layered Transition Metal Dichalcogenides for Sustainable Energy Storage and the Intelligent Trends in Data Analytics

Advanced Science, EarlyView.
This review comprehensively summarizes the atomic defects in TMDs for their applications in sustainable energy storage devices, along with the latest progress in ML methodologies for high‐throughput TEM data analysis, offering insights on how ML‐empowered microscopy facilitates bridging structure–property correlation and inspires knowledge for precise ...
Zheng Luo, Ying Yang, Zizhen Fu, Fengqi Liu, Susu Fang, Kele Xu, Shanshan Wang   +6 more
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

A new CO₂ refrigeration system with two-phase ejector and parallel compression for supermarkets. [PDF]

Heliyon
Tashtoush B, Sahli H, Elakhdar M, Megdouli K, Nehdi E.   +4 more
europepmc   +1 more source