Results 111 to 120 of about 1,303,094 (262)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

COMPARISON BETWEEN EULERIAN AND VOF MODELS FOR TWO-PHASE FLOW ASSESSMENT IN VERTICAL PIPES

CT&F Ciencia, Tecnología & Futuro
The appropriate characterization of the two-phase flow has been recently considered as a topic of interest at industrial level. The Computational Fluid Dynamics (CFD) is one of the techniques used for this analysis.
Esteban Guerrero, Felipe Muñoz, Nicolás Ratkovich   +2 more
doaj  

Multiscale Characterization of Flow Instability for Gas-Liquid Two-Phase Flow. [PDF]

Entropy (Basel)
Sun QM, Yu QC, Ba D, Du Y.
europepmc   +1 more source

Dual-Modal Electrical Imaging of Two-Phase Flow-Experimental Evaluation of the State Estimation Approach. [PDF]

Sensors (Basel), 2023
Arif MZ, Seppänen A, Kolehmainen V, Vauhkonen M.   +3 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Multistructural and Multiscale Instability Characterization of Gas-Liquid Two-Phase Flow with MRA-CMESSE. [PDF]

Entropy (Basel)
Sun QM, Yu QC, Ba D.
europepmc   +1 more source

Computational fluid dynamics simulation of two-phase flow patterns in a serpentine microfluidic device. [PDF]

Sci Rep, 2023
Amini Y, Ghazanfari V, Heydari M, Shadman MM, Khamseh AG, Khani MH, Hassanvand A.   +6 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Investigation of drag models for simulation of gas-liquid two-phase flow systems. [PDF]

Sci Rep
Adzaklo SY, Sarkodie K, Agyei E, Yamoah S, Asiedu NY.   +4 more
europepmc   +1 more source

Numerical simulation of slug flow in pipelines using drift flux constitutive equations for gas-viscous oil two-phase flow. [PDF]

Heliyon, 2023
Pugliese V, Buelvas A, Pupo-Roncallo O.
europepmc   +1 more source