Results 151 to 160 of about 24,725,371 (235)

Analysis of gas-solid two-phase flow and structure optimization of mobile shot blasting machine recovery device. [PDF]

Sci Rep, 2022
Zhang Y, Fu X, Men X, Pan Y, Zhang T, Jiang Z.   +5 more
europepmc   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Numerical Evaluation and Assessment of Key Two-Phase Flow Parameters Using Four-Sensor Probes in Bubbly Flow. [PDF]

Sensors (Basel)
Monrós-Andreu G, Peña-Monferrer C, Martínez-Cuenca R, Torró S, Chiva S.   +4 more
europepmc   +1 more source

Performance Prediction of Erosive Wear of Steel for Two-Phase Flow in an Inverse U-Bend. [PDF]

Materials (Basel), 2022
Rahman S, Khan R, Niazi UM, Legutko S, Khan MA, Ahmed BA, Petrů J, Hajnyš J, Irfan M.   +8 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Safety, pharmacokinetics, and pharmacodynamics of Dexmedetomidine two-phase flow atomization in healthy subjects: a randomized, parallel study. [PDF]

BMC Anesthesiol
Lian Y, Luo H, Yang Z, He J, Chen H, Sun Y.   +5 more
europepmc   +1 more source

Electrical Impedance Tomography of Industrial Two-Phase Flow Based on Radial Basis Function Neural Network Optimized by the Artificial Bee Colony Algorithm. [PDF]

Sensors (Basel), 2023
Zhu Z, Li G, Luo M, Zhang P, Gao Z.
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Dataset of two-phase flow in a horizontal pipe: synchronized measurements of acceleration, pressure, void fraction and high-velocity camera. [PDF]

Data Brief
das Neves DA, Vieira SC, Cenzi JR, Fabro AT, Foresti BP, Castro MS.   +5 more
europepmc   +1 more source

Machine learning applications to predict two-phase flow patterns. [PDF]

PeerJ Comput Sci, 2021
Arteaga-Arteaga HB, Mora-Rubio A, Florez F, Murcia-Orjuela N, Diaz-Ortega CE, Orozco-Arias S, delaPava M, Bravo-Ortíz MA, Robinson M, Guillen-Rondon P, Tabares-Soto R.   +10 more
europepmc   +1 more source