Results 41 to 50 of about 1,247,885 (263)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Droplet Manipulations in Two Phase Flow Microfluidics
Micromachines, 2015 Even though droplet microfluidics has been developed since the early 1980s, the number of applications that have resulted in commercial products is still relatively small.
Arjen M. Pit +2 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
FluidsBubbly flow is a flow regime common in many industrial applications involving heat and mass transfer, such as reactors, cooling systems, and separation units.
Giulio Tribbiani +5 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The Influence of Direction & Solid Loading Ratio on Two Phase Flow Energy
مجلة النهرين للعلوم الهندسية, 2010 This research investigates the influence of solid loading ratio , Reynolds number & angle of flow direction change on minor losses coefficient for two-phase flow type gas-solid through an orifice by manufacturing a special apparatus with solving the ...
Ahmed Adeeb AbdulWahid
doaj
Severe slugging mitigation by utilizing the active use of choke control valve
Applied Ocean ResearchOne of the common flow assurance issues in offshore production facilities is riser-based severe slugging. Severe slugging is a cyclic process that occurs in the late life of reservoirs when there is not enough energy available in the system to push the ...
V Banjara +3 more
doaj +1 more source
Sensors, 2016 The parameters of gas-liquid two-phase flow bubbles in field coalbed methane (CBM) wells are of great significance for analyzing coalbed methane output, judging faults in CBM wells, and developing gas drainage and extraction processes, which stimulates ...
Chuan Wu +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source