Results 71 to 80 of about 1,303,094 (262)
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
STABILITY OF TWO-PHASE FLOW MODELS [PDF]
Summary: We study two-phase flow models. The chunk mix model of the two-phase flow equations is analyzed by a characteristic analysis. The model discussed herein has real characteristic values for all physically acceptable states and except for a set of measure zero has a complete set of characteristic vectors in state space.
openaire +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
A Mathematical Model for The Performance of Solar Heating Driven Bubble Pumps
A mathematical model of the bubble pump is established by employing the governing equations; the continuity, momentum and energy equations. The model was used to evaluate the performance of the pump under different geometrical and operational conditions.
Khaled Elshawesh +2 more
doaj
Fluctuating Characteristics of Two-Phase Air-Water Slug Flow in Pressurized Pipelines [PDF]
Two-phase gas-liquid flows occur in a wide variety of situations, e.g., in chemical processing, power generation, water supply systems, and petroleum industry. The study of two-phase fluid flows is of great importance in hydraulic engineering.
Abdorreza Kabiri-Samani
doaj
This study aims to investigate the horizontally oriented internal two-phase flow induced force fluctuations. Gas-liquid two-phase flow experiments were conducted on 90 degree pipe bend, oriented horizontal-downwardly. Multiple tri-axial force transducers
Shuichiro MIWA +6 more
doaj +1 more source

