Results 121 to 130 of about 18,935,794 (304)

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Assortative matching through signals [PDF]

open access: yes
We model signalling in two-sided sequential search with heterogeneous agents and transferable utility. Search via meetings is time-consuming and thereby costly due to discounting. Search via signals is costless, so that agents can avoid almost all search
Friedrich Poeschel
core  

Two-Sided Matching with Resource-Regional Caps

open access: yesCoRR
We study two-sided many-to-one matching problems under a novel type of distributional constraints, resource-regional caps. In the context of college admissions, under resource-regional caps, an admitted student may be provided with a unit of some resource through a college, which belongs to a region possessing some amount of this resource.
Garrido-Lucero, Felipe   +3 more
openaire   +4 more sources

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Credible Group Stability in Many-to-Many Matching Problems [PDF]

open access: yes
It is known that in two-sided many-to-many matching problems, pairwise stable matchings may not be immune to group deviations, unlike in many- to-one matching problems (Blair 1988). In this paper, we show that pairwise stability is equivalent to credible
Hideo Konishi, M. Utku Ünver
core  

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Monotonicity and Nash implementation in matching markets with contracts [PDF]

open access: yes
We consider general two-sided matching markets, so-called matching with contracts markets as introduced by Hatfield and Milgrom (2005) and analyze (Maskin) monotonic and Nash implementable solutions.
Claus-Jochen Haake, Bettina Klaus
core  

Essays in two-sided platforms [PDF]

open access: yes, 2008
In the first chapter we present a critical survey of the literature on platforms and two-sided markets. First, we introduce two general models, called the “Armstrong’s model” and the “Rochet-Tirole’s model”, to understand the main issues that arise in
Viecens, María Fernanda
core   +1 more source

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