Results 231 to 240 of about 1,618,729 (319)

A Review of Neural Network-Based Image Noise Processing Methods. [PDF]

Sensors (Basel)
Volkov AA, Kozlov AV, Cheremkhin PA, Rymov DA, Shifrina AV, Starikov RS, Nebavskiy VA, Petrova EK, Zlokazov EY, Rodin VG.   +9 more
europepmc   +1 more source

Genetic Modifiers of Parkinson's Disease: A Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the associations of LRRK2 p.G2019S, GBA1 p.N409S, polygenic risk scores (PRS), and APOE E4 on PD penetrance, risk, and symptoms. Methods We conducted a US‐based observational case–control study using data from the 23andMe Inc. and Fox Insight Genetic Substudy (FIGS) databases.
Matthew J. Kmiecik, Michael V. Holmes, Pierre Fontanillas, Giulietta M. Riboldi, Ruth B. Schneider, Jingchunzi Shi, Anna Guan, Susana Tat, Steven Micheletti, Keaton Stagaman, Josh Gottesman, David A. Hinds, Joyce Y. Tung, 23andMe Research Team, Stella Aslibekyan, Lucy Norcliffe‐Kaufmann   +15 more
wiley   +1 more source

Robust Pose Estimation and Size Classification for Unknown Dump Truck Using Normal Distribution Transform. [PDF]

Sensors (Basel)
Imai K, Watanabe K, Okabe H, Matsuyama T, Shirao A, Ito T.   +5 more
europepmc   +1 more source

Longitudinal Study of Salivary Biomarkers in the Definition of Clinico‐Molecular Progression of Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
Longitudinal changes in salivary biomarkers in Parkinson’s disease (PD) from early (T0) to 4‐year follow‐up (T1), quantified by ELISA: oligomeric and total α‐synuclein, total and phosphorylated tau, MAP1LC3B (autophagy), and TNFa (inflammation). Blue arrows indicate direction of change at T1 vs T0 (up = increase; down = decrease).
Maria Ilenia De Bartolo, Daniele Belvisi, Matteo Costanzo, Claudia Caturano, Francesco Emanuele Bellomi, Carolina Cutrona, Flavia Aiello, Giorgio Leodori, Massimo Marano, Romina Mancinelli, Antonella Conte, Giovanni Fabbrini, Alfredo Berardelli, Giorgio Vivacqua   +13 more
wiley   +1 more source

Discovering heterogeneous treatment effects on slope-based endpoints in chronic kidney disease trials. [PDF]

BMC Med Res Methodol
Pan T, Tian L, Kurella Tamura M, Montez-Rath M, Charu V.   +4 more
europepmc   +1 more source

Bias Transmission In Two-Stage Estimation [PDF]

Christophe Muller, Tae-Hwan Kim
core  

Assessing a Mitochondrial Disease Treatment via a Novel Statistical Technique for Accelerometer Data

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Therapeutic development for mitochondrial diseases, rare genetic disorders with pathogenic defects of oxidative phosphorylation, is hindered by unsatisfactory outcome measures. To address this problem, we provide the first clinical application of a novel, bias‐adjusted outcome measure of acceleration across a range of subjects ...
Ian W. McKeague, Kristin Engelstad, Yue Ge, Amber Tucker, Shufang Li, Jasim Uddin, Ziwei Zhao, John L. P. Thompson, Michio Hirano   +8 more
wiley   +1 more source

Point estimation, confidence intervals, and P‐values for optimal adaptive two‐stage designs with normal endpoints [PDF]

Jan Meis, Maximilian Pilz, Björn Bokelmann, Carolin Herrmann, Geraldine Rauch, Meinhard Kieser   +5 more
openalex   +1 more source

Bioarcheological Perspectives on the Timing of Adolescence in Rural Avar-Age Austria, 7th-9th Centuries ce. [PDF]

Am J Biol Anthropol
Klostermann P, Lewis M, Berner M, Eggers S, Tobias B, Wang K, Hofmanová Z, Pany-Kucera D.   +7 more
europepmc   +1 more source

Characteristics of Cerebral Palsy in the Midwestern US

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral palsy (CP) is the most common lifelong motor disability worldwide. Yet, data is limited on how CP manifests in the US. Our objective was to characterize and determine factors affecting functional outcomes in a large population of young people with CP in the Midwestern US.
Susie Kim, Kelsey Steffen, Lauren Gottschalk‐Henneberry, Jennifer Miros, Amy Robichaux‐Viehoever, Karen Taca, Bhooma R. Aravamuthan   +6 more
wiley   +1 more source