Results 21 to 30 of about 22,687,746 (256)

Conditionally unbiased estimation in phase II/III clinical trials with early stopping for futility [PDF]

open access: yes, 2013
Seamless phase II/III clinical trials combine traditional phases II and III into a single trial that is conducted in two stages, with stage 1 used to answer phase II objectives such as treatment selection and stage 2 used for the confirmatory analysis ...
Todd, Susan C.   +6 more
core   +1 more source

Estimation of Tropical Cyclone Intensity via Deep Learning Techniques from Satellite Cloud Images

open access: yesRemote Sensing, 2023
Estimating the intensity of tropical cyclones (TCs) is usually involved as a critical step in studies on TC disaster warnings and prediction. Satellite cloud images (SCIs) are one of the most effective and preferable data sources for TC research. Despite
Biao Tong   +5 more
doaj   +1 more source

Two-stage re-estimation adaptive design: a simulation study

open access: yesEpidemiology, Biostatistics and Public Health, 2022
  Background: adaptive clinical trial design has been proposed as a promising new approach to improve the drug discovery process. Among the many options available, adaptive sample size re-estimation is of great interest mainly because of its ...
Francesca Galli, Luigi Mariani
doaj  

Millimeter-Wave Based Localization Using a Two-Stage Channel Estimation Relying on Few-Bit ADCs

open access: yesIEEE Open Journal of the Communications Society, 2021
Benefiting from the high resolution in beamspace, millimeter wave (mmwave) communication has been regarded as a high-accuracy localization solution, where the location information is embedded in the channel via angle and time delay, for example.
Kunlun Li   +2 more
doaj   +1 more source

Two-Stage Limited-Information Estimation for Structural Equation Models of Round-Robin Variables

open access: yesStats
We propose and demonstrate a new two-stage maximum likelihood estimator for parameters of a social relations structural equation model (SR-SEM) using estimated summary statistics (Σ^) as data, as well as uncertainty about Σ^ to obtain robust inferential ...
Terrence D. Jorgensen   +2 more
doaj   +1 more source

A Novel Two-Stage Illumination Estimation Framework for Expression Recognition

open access: yesThe Scientific World Journal, 2014
One of the critical issues for facial expression recognition is to eliminate the negative effect caused by variant poses and illuminations. In this paper a two-stage illumination estimation framework is proposed based on three-dimensional representative ...
Zheng Zhang, Guozhi Song, Jigang Wu
doaj   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben   +4 more
wiley   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk   +10 more
wiley   +1 more source

On Two-Stage Non-Parametric Estimation [PDF]

open access: yes, 1963
1 online resource (PDF, 46 pages)Yen, Elizabeth Y. H.. (1963). On Two-Stage Non-Parametric Estimation.
Yen, Elizabeth Y. H., Elizabeth Y. Yen
core   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin   +17 more
wiley   +1 more source

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