Optimization of Moving Cone Liner Dynamics and Health Status Prediction for Cone Crushers. [PDF]
Sensors (Basel)Li M, Fu R, Wu D, Zhao L.
europepmc +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
DOSET: dose optimization with simultaneous efficacy and toxicity evaluation, motivated by a first-in-human phase I CAR T lymphoma trial. [PDF]
ESMO OpenHu X +4 more
europepmc +1 more source
Generalized Decision Rule Approximations for Stochastic Programming via Liftings [PDF]
Stochastic programming provides a versatile framework for decision-making under uncertainty, but the resulting optimization problems can be computationally demanding.
Wolfram Wiesemann +2 more
core
Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann +17 more
wiley +1 more source
Tensile behavior evaluation of two-stage concrete using an innovative model optimization approach
Reviews on Advanced Materials ScienceAmin Muhammad Nasir +5 more
doaj +1 more source
Coverage Optimization Strategy for Wireless Sensor Networks Based on Improved Northern Goshawk Optimization Algorithm. [PDF]
Biomimetics (Basel)Wang S +5 more
europepmc +1 more source
Hidden Convexity in Partially Separable Optimization [PDF]
The paper identifies classes of nonconvex optimization problems whose convex relaxations have optimal solutions which at the same time are global optimal solutions of the original nonconvex problems. Such a hidden convexity property was so far limited to
Laurent, M., Ben-Tal, A., Hertog, D. den
core +1 more source
Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source
Deblurring structural edges in variable thickness topology optimization via density-gradient-informed projection. [PDF]
Struct Multidiscipl OptimStankiewicz G, Dev C, Steinmann P.
europepmc +1 more source