Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz +9 more
wiley +1 more source
Benders Decomposition Using Graph Modeling and Multi-Parametric Programming. [PDF]
Brahmbhatt P +3 more
europepmc +1 more source
ABSTRACT Objective This analysis evaluates the effect of successful reperfusion on functional outcomes after MT, stratified by admission National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT Score (ASPECTS) as surrogates for clinical‐core mismatch, using multicenter registry data.
Felix Schlicht +53 more
wiley +1 more source
Continuous fabrication of Janus liquid crystal elastomer fibers with programmable actuation. [PDF]
Xu J +11 more
europepmc +1 more source
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source
Integrated Design and Scheduling of Hydrogen Processes under Uncertainty: A Quantile Neural Network Approach. [PDF]
Ghilardi LMP +3 more
europepmc +1 more source
AI-driven emergency logistics network deployment in dynamic environments. [PDF]
Mei L, Chenjing Y, Sha S.
europepmc +1 more source
Optimizing patient flow logistics: strategic challenges, tactical solutions, and future directions. [PDF]
Zamani H, Parvaresh F, Isfahani MN.
europepmc +1 more source
A modular PLC simulation method for virtual replication of a cost-effective industrial automation laboratory. [PDF]
Al-Yaman M +4 more
europepmc +1 more source
Effects of a bidirectional interoperability between electronic health records and smart infusion pumps in hospital settings: a systematic review. [PDF]
Kuitunen S +5 more
europepmc +1 more source

