Results 91 to 100 of about 159,833 (300)

Distributionally Robust Chance Constrained Geometric Optimization [PDF]

, 2018
In this talk, we discuss distributionally robust geometric programs with individual and joint chance constraints. We consider three groups of uncertainty sets, namely uncertainty sets with known two first order moments information, uncertainty sets ...
Lisser, Abdel
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Cooperative Operation Optimization for Multi-region Hydrogen-Integrated Integrated Energy System Based on Hybrid Wasserstein Two-Stage Distributionally Robust

Zhongguo dianli
An integrated energy system (IES) coupled with hydrogen energy is significantly influenced by source-load uncertainties when operating alone. Traditional robust optimization techniques are overly conservative, which impedes the economic performance.
Xiaoqiang DING, Zhi YUAN, Ji LI
doaj   +1 more source

Distributionally robust optimization model of active distribution network considering uncertainties of source and load

Journal of Modern Power Systems and Clean Energy, 2019
To ensure the safety and reliability of the distribution network and adapt to the uncertain development of renewable energy sources and loads, a two-stage distributionally robust optimization model is proposed for the active distribution network (ADN ...
Lei Dong, Jia Li, Tianjiao Pu, Naishi Chen   +3 more
doaj   +1 more source

Robust Counterparts of Inequalities Containing Sums of Maxima of Linear Functions [PDF]

This paper adresses the robust counterparts of optimization problems containing sums of maxima of linear functions and proposes several reformulations. These problems include many practical problems, e.g.
Gorissen, B.L., Hertog, D. den
core   +1 more source

Stochastic programming models and methods for portfolio optimization and risk management [PDF]

, 2012
This project is focused on stochastic models and methods and their application in portfolio optimization and risk management. In particular it involves development and analysis of novel numerical methods for solving these types of problem.
Meskarian, Rudabeh
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Two-Stage Distributionally Robust Optimal Scheduling for Integrated Energy Systems Considering Uncertainties in Renewable Generation and Loads

Mathematics
To effectively account for the impact of fluctuations in the power generation efficiency of renewable energy sources such as photovoltaics (PVs) and wind turbines (WTs), as well as the uncertainties in load demand within an integrated energy system (IES),
Keyong Hu, Qingqing Yang, Lei Lu, Yu Zhang, Shuifa Sun, Ben Wang   +5 more
doaj   +1 more source

Hidden Convexity in Partially Separable Optimization [PDF]

The paper identifies classes of nonconvex optimization problems whose convex relaxations have optimal solutions which at the same time are global optimal solutions of the original nonconvex problems. Such a hidden convexity property was so far limited to
Laurent, M., Ben-Tal, A., Hertog, D. den
core   +1 more source