Results 111 to 120 of about 367,886 (378)

Vorticity‐Facilitated Platelet Aggregation: a High Expansion‐Ratio Stenotic Microfluidic Platform Unravels the Role of Complex Flow Dynamics in Arterial Thrombosis

open access: yesAdvanced Healthcare Materials, EarlyView.
This study reveals how vorticity—a swirling flow pattern—enhances platelet aggregation and thrombus formation in high‐shear conditions. Using a custom microfluidic model, it is shows that vorticity promotes vWF–GPIbα interactions and calcium signaling, providing new insights into thrombosis mechanobiology and informing safer blood‐contacting medical ...
Jianfang Ren   +13 more
wiley   +1 more source

A conceptual study of the potential for automotive-derived and free-piston Stirling engines in 30- to 400-kilowatt stationary power applications [PDF]

open access: yes
The technical feasibility of applying automotive-derived kinematic and free-piston Stirling engine concepts for stationary applications was explored. Automotive-derived engines offer cost advantages by providing a mature and developd engine technology ...
Chen, H. S., Dineen, J., Vatsky, A.
core   +1 more source

Immunomodulation With Local, Sustained Delivery of Pituitary Adenylate Cyclase Activating Polypeptide Results in Improved Functional Recovery in Stroke‐Injured Mice

open access: yesAdvanced Healthcare Materials, EarlyView.
The tissue and functional benefits are demonstrated with local, sustained delivery of an anti‐inflammatory peptide, pituitary adenylate cyclase‐activating polypeptide (PACAP), for stroke treatment in a mouse model. Prolonged PACAP treatment modulated astrocyte and microglia toward pro‐reparative phenotypes, enhanced neuroprotection and preservation of ...
Eric Ho   +7 more
wiley   +1 more source

Energetics and performance of a microscopic heat engine based on exact calculations of work and heat distributions

open access: yes, 2009
We investigate a microscopic motor based on an externally controlled two-level system. One cycle of the motor operation consists of two strokes. Within each stroke, the two-level system is in contact with a given thermal bath and its energy levels are ...
Artem Ryabov   +14 more
core   +1 more source

Lymphoid and CXCR4 Cell Targeted Lipid Nanoparticles Facilitate HIV‐1 Proviral DNA Excision

open access: yesAdvanced Healthcare Materials, EarlyView.
Advancements in ART improve HIV‐1 patient outcomes but are unable to eliminate latent viral DNA. To address this, CXCR4‐targeted lipid nanoparticles (T‐LNPs) for delivering CRISPR‐Cas9 to excise HIV‐1 DNA in infected cells are developed. These T‐LNPs achieve ≈60% HIV‐1 DNA excision efficacy in blood and splenic tissue, demonstrating promise for ...
Sudipta Panja   +6 more
wiley   +1 more source

Analysis of Combustion Process in Industrial Gas Engine with Prechamber-Based Ignition System

open access: yesEnergies, 2018
Application of a pre-combustion chamber (PCC) ignition system is one of the methods to improve combustion stability and reduce toxic compounds emission, especially NOx.
Rafał Ślefarski   +4 more
doaj   +1 more source

Evaluation of facilities performance on students’ satisfaction in Northern Nigerian Universities [PDF]

open access: yes, 2017
Performance evaluation of academic facilities of HEIs is very critical to educational effectiveness. Presently, there is limited or no research/data in Nigeria to assess how extensively the use of or lack of academic facilities benchmarking practices ...
Abdullahi, Isa
core  

Boosting capacitive blue-energy and desalination devices with waste heat

open access: yes, 2014
We show that sustainably harvesting 'blue' energy from the spontaneous mixing process of fresh and salty water can be boosted by varying the water temperature during a capacitive mixing process.
Härtel, Andreas   +2 more
core   +1 more source

An Organ‐on‐Chip Platform for Strain‐Controlled, Tissue‐Specific Compression of Cartilage and Mineralized Osteochondral Interface to Study Mechanical Overloading in Osteoarthritis

open access: yesAdvanced Healthcare Materials, EarlyView.
A mechanically active OsteoChondral Unit (OCU)‐on‐Chip platform mimicking the OCU's functional anatomy and the strain gradient across the osteochondral interface is presented. Upon compartment‐specific hyperphysiological compression, the model replicates mechanisms observed in osteoarthritis (OA) progression, such as calcium crystal accumulation ...
Andrea Mainardi   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy