Results 181 to 190 of about 121,111 (354)

Ultra‐High Friction and Adhesion in Hydrogel Layer Driven by Wet‐to‐Dry Transition Dynamics

open access: yesAdvanced Science, EarlyView.
This work reveals a critical wet‐to‐dry transition in polyacrylamide hydrogel layers that induces volumetric shrinkage, resulting in enhanced interfacial contact and dramatically increased friction and adhesion. Leveraging this transition enables strong, reversible gripping on diverse surfaces, offering new insights for hydrogel‐based gripping ...
Chenxu Liu   +11 more
wiley   +1 more source

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

open access: yesAdvanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge   +21 more
wiley   +1 more source

Nurr1 Orchestrates Claustrum Development and Functionality

open access: yesAdvanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan   +12 more
wiley   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

open access: yesAdvanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy