Results 191 to 200 of about 121,111 (354)

TRIM56 Aggravates Cerebral Ischemia‐Reperfusion Injury via Inhibiting KLF4‐Activated Ferroptosis Signaling

Advanced Science, EarlyView.
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang, Shuang Li, Man Li, Wenke Zhou, Jianqing Zhang, Zhenfu Wu, Zhaoqi Mao, Juan Wan, Xinhao Tang, Baoping Zheng, Qiang Liu, Zhendong Li, Xiaobing Jiang, Qingping Wu, Youfan Ye, Haijun Wang   +15 more
wiley   +1 more source

Thermodynamics based modeling of various in-cylinder processes and spark ignition engine cycle with a focus on sub-models assessment. [PDF]

Sci Rep
Chandrakar CK, Varma PS, Mittal M.
europepmc   +1 more source

Postoperative Stress Accelerates Atherosclerosis Through Inflammatory Remodeling of the HDL Proteome and Impaired Reverse Cholesterol Transport

Advanced Science, EarlyView.
The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher, Victoria Lorant, Valerie Rochon, Abigail Carter, Cameron Stotts, My‐Anh Nguyen, Thomas Laval, Christina Emerton, Nathan Joyce, Nysa Vinayak, Marlena Scaffidi, David Cook, Katey J. Rayner, Rebecca C. Auer, Scott M. Gordon, Mireille I. Ouimet   +15 more
wiley   +1 more source

Comparative Analysis of Real-Driving Emission Characteristics of Euro 7 Hybrid Electric Vehicles at Varied Ambient Temperatures. [PDF]

ACS Omega
Shi L, Qiu J, Cui S, Yang Y, Ye L, Jin H, Xu X.   +6 more
europepmc   +1 more source

Numerical analysis of combustion and transient heat transfer processes in a two-stroke SI engine

, 2010
Fernando Illán Gómez, M. Alarcón
openalex   +2 more sources

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

Advanced Science, EarlyView.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu, Yajie Zhang, Yushi Tang, Hongli Hu, Ying Zhang, Junwen Xue, Hao Wang, Yecheng Wang, Chunfeng Liu, Jia Jia, Jian Cheng, Yongjun Cao   +11 more
wiley   +1 more source

Fuel-Powered Soft Actuators: Emerging Strategies for Autonomous and Miniaturized Robots. [PDF]

Nanomicro Lett
Zhou C, Li Z, Wei H, Zhang G, Zhang F, Zhou X, Hu H, Cheng G, Ding J, Kim SH, Baughman RH, Hu X.   +11 more
europepmc   +1 more source

Performance of a Two-Stroke-Cycle Gasoline Injection Engine

, 1960
Fujio NAGAO, Takasi KOBAYAKAWA, Ryuzo OKUNO, Mai MATSUMOTO   +3 more
openalex   +2 more sources

Mammalian Proteome Profiling Reveals Readers and Antireaders of Strand‐Symmetric and ‐Asymmetric 5‐Hydroxymethylcytosine‐Modifications in DNA

Advanced Science, EarlyView.
We investigate by proteomics studies how strand‐symmetric and ‐asymmetric cytosine 5‐modifications in DNA are selectively recognized by the nuclear proteome. Using promoter probes with defined modification patterns, we identify tissue‐specific reader proteinsincluding MYC, MAX, and RFX5that discriminate 5‐hydroxymethylcytosine symmetry and sequence ...
Lena Engelhard, Zeyneb Vildan Cakil, Marlon S. Zambrano‐Mila, Simone Eppmann, Tye Gonzalez, Rasmus Linser, Petra Janning, Sidney Becker, Daniel Summerer   +8 more
wiley   +1 more source

Influence of carbon free gaseous ammonia induction on combustion, performance and emissions in an agricultural diesel engine operated on dual fuel mode. [PDF]

Sci Rep
Khayum N, Suraya S, Nandakishora Y, Shaik JH, Barik D, Dennison MS, Dinesh A, Rajendran S.   +7 more
europepmc   +1 more source