3D Brain Vascular Niche Model Captures Glioblastoma Infiltration, Dormancy, and Gene Signatures
This study developed a 3D brain vascular niche model that capture the key features of glioblastoma including perivascular infiltration, gene signature, dormancy and chemo resistance, by comparing 3D model with in vivo condition using identical glioma stem cells.
Vivian K. Lee+10 more
wiley +1 more source
Effect of Auxiliary Hydrogen Injection in the Prechamber on the Combustion Process of a Natural Gas Engine. [PDF]
Yang X+5 more
europepmc +1 more source
Reinforcing Stromal Cell Spheroid Through Red‐Light Preconditioning for Advanced Vascularization
This study presents a novel approach to enhance stromal cell therapy for myocardial infarction by combining OLED‐based photobiomodulation (OPBM) preconditioning with 3D spheroid culture of hADSCs. The engineered spheroids improve angiogenesis, arterialization, and cardiac function in vivo, offering a next‐generation therapeutic strategy to overcome ...
Yu‐Jin Kim+12 more
wiley +1 more source
Establish operating conditions for optimal output characteristics in reactivity controlled combustion engine. [PDF]
Muniyappan S, Krishnaiah R.
europepmc +1 more source
Mechanical Biomimetic Nanocomposites for Multidimensional Treatment of Arterial Thrombosis
In this study, a mechanical biomimetic nanocomposite is developed, guided by photoacoustic imaging, to achieve highly efficient and safe thrombolysis through the synergistic effects of photothermal therapy and pharmacological intervention. Most notably, the nanoparticle improves the microenvironment of arterial thrombi, marked by high shear stress and ...
Ying Li+6 more
wiley +1 more source
Engine performance and emission optimization with waste cooking oil biodiesel/diesel blend using ANN and RSM techniques coupled with ACKTR-DE and HHO algorithms. [PDF]
Biberci MA, Çelik MB, Ozhuner E.
europepmc +1 more source
Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang+4 more
wiley +1 more source