Results 31 to 40 of about 119,428 (354)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Development of a Two-Stroke Cycle Engine for Use in the Agricultural Aviation Sector

Journal of Aerospace Technology and Management, 2020
Reciprocating internal combustion engines have wide application in agricultural, recreational and experimental aircraft, resulting from their low cost and less complex maintenance compared to other engines.
Samara Herrmann, Macklini Dalla Nora, Thompson Diordinis Metzka Lanzanova   +2 more
doaj   +3 more sources

Conversion of four-stroke engines to six-stroke engines using epicyclic gearing in camshaft modification [PDF]

Mechanical Sciences
In this study, a compact, single-cylinder, spark-ignition, four-stroke engine commonly used in power generators is converted into a six-stroke engine. This conversion employed the free-stroke Kelem model, one of the six-stroke engine approaches described
E. Arabacı, M. Akar
doaj   +1 more source

Design and development of auxiliary components for a new two-stroke, stratified-charge, lean-burn gasoline engine [PDF]

, 2005
A unique stepped-piston engine was developed by a group of research engineers at Universiti Teknologi Malaysia (UTM), from 2003 to 2005. The development work undertaken by them engulfs design, prototyping and evaluation over a predetermined period of ...
Abdul Aziz, Azhar, Abdul Latif, Zulkarnain, Abu Bakar, Rosli, Mohd. Noor, Alias, Mohd. Rohani, Jafri, Saat, Aminuddin   +5 more
core  

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

A comparative study on mean value modelling of two-stroke marine diesel engine [PDF]

, 2009
In the present paper, two mean value modelling approaches of varying complexity, capable of simulating two-stroke marine Diesel engines, are presented. Both approaches were implemented in the computational environment of MATLAB Simulink®. Simulation runs
Theotokatos, Gerasimos
core  

Altered Dynamic Functional Network Connectivity in Post‐Stroke Aphasia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Previous studies examining post‐stroke aphasia (PSA) patients via resting‐state functional magnetic resonance imaging (rs‐fMRI) have predominantly focused on static functional connectivity. In contrast, the current investigation aims to elucidate the alterations in dynamic functional network connectivity (dFNC) among PSA patients ...
Guihua Xu, Yongsheng Wu, Junyu Qu, Rui Zhu, Wenwen Xu, Jiaxiang Xin, Dawei Wang   +6 more
wiley   +1 more source

Selected Issues of the Indicating Measurements in a Spark Ignition Engine with an Additional Expansion Process

Applied Sciences, 2017
The paper presents the results of research on the turbocharged spark ignition engine with additional exhaust expansion in a separate cylinder, which is commonly known as the five-stroke engine.
Marcin Noga
doaj   +1 more source

Design and development of piston-controlled intake port for 4-stroke engine [PDF]

, 2008
In a two stroke engine, piston control the intake port opening and closing that combine the intake and compression stroke in 1800 crank rotation. The operational concept of two stroke engine is applied to the existing four stroke engine cylinder head ...
Amran, Kaharudin
core  

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source