Results 81 to 90 of about 28,714,507 (293)
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Diffusion Limit for Single-Server Retrial Queues with Renewal Input and Outgoing Calls
This paper studies a single-server retrial queue with two types of calls (incoming and outgoing calls). Incoming calls arrive at the server according to a renewal process, and outgoing calls of N−1 (N≥2) categories occur according to N−1 independent ...
Anatoly Nazarov +3 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Employee voice: speaking up in organisation as a correlate of employee productivity in oil and gas industry - an empirical investigation from Nigeria [PDF]
The understanding and interpretation of voice have been given critical attention among researchers, practitioners in recent years. The firm believes of the workforce that they can openly express their personal opinion and concerns to higher authority in ...
Olusegun Emmanuel Akinwale
doaj +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Network coding (NC) compresses two traffic flows with the aid of low-complexity algebraic operations, hence holds the potential of significantly improving both the efficiency of wireless two-way relaying, where each receiver is collocated with a ...
Chen, Wei, Hanzo, Lajos, Cao, Zhigang
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Rank formulas for certain products of matrices [PDF]
Ahlswede R, Cai N. Rank formulas for certain products of matrices. Applicable Algebra in Engineering, Communication and Computing. 1993;4(4):253-261.For two matrix operations, called quasi-direct sum and quasi-outer product, we determine their deviations
Cai, Ning, Ahlswede, Rudolf
core +1 more source
Multiserver Retrial Queue with Two-Way Communication and Synchronous Working Vacation
This work investigates a two-way communication retrial queue with synchronous working vacation and a constant retrial policy. During the idle time, a server makes an outgoing call after a random length.
Tzu-Hsin Liu +3 more
doaj +1 more source

