Results 161 to 170 of about 24,764,004 (235)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Application of Array Imaging Algorithms for Water Holdup Measurement in Gas-Water Two-Phase Flow Within Horizontal Wells. [PDF]

Sensors (Basel)
Guo H, Li A, Sun Y, Yu L, Peng W, Ouyang M, Wang D, Guo Y.   +7 more
europepmc   +1 more source

Flow Pattern Identification of Oil-Water Two-Phase Flow Based on SVM Using Ultrasonic Testing Method. [PDF]

Sensors (Basel), 2022
Su Q, Li J, Liu Z.
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Optimization of refracturing timing in tight oil reservoirs based on an oil water two phase flow model. [PDF]

Sci Rep
Zhou Q, Dai R, Chen L, Wu C, Luo S.
europepmc   +1 more source

Numerical Study on the Coagulation and Breakage of Nanoparticles in the Two-Phase Flow around Cylinders. [PDF]

Entropy (Basel), 2022
Shi R, Lin J, Yang H.
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Nonlinear bubble dynamics in cryogenic two-phase flow under ultrasonic excitation considering mass transfer. [PDF]

Ultrason Sonochem
Zhang J, Zhang Y, Chen Y, Rui X, Zheng C, Wu Y, Yang J, Gao H, Qi L.   +8 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

RETRACTED: Davarpanah, A. Parametric Study of Polymer-Nanoparticles-Assisted Injectivity Performance for Axisymmetric Two-Phase Flow in EOR Processes. <i>Nanomaterials</i> 2020, <i>10</i>, 1818. [PDF]

Nanomaterials (Basel)
Davarpanah A.
europepmc   +1 more source