Results 81 to 90 of about 1,385,907 (313)

Upscaling multi-component two-phase flow in porous media with partitioning coefficient [PDF]

open access: yes, 2011
This paper deals with the upscaling of multicomponents two-phase flow in porous media. In this paper, chemical potential equilibrium at the interface between both phases is assumed to be described by a linear partitioning relationship such as Raoult or ...
Quintard, Michel   +5 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Single-phase flow and flow boiling of water in horizontal rectangular microchannels [PDF]

open access: yes, 2013
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel UniversityThe current study is part of a long term experimental project devoted to investigating single-phase flow pressure drop and heat transfer, flow boiling ...
Mirmanto
core  

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Simulation of Drag Reducer Polymer (DRP) for Single and Annular Two Phase Flow in Horizontal Pipe

open access: yesJurnal Rekayasa Kimia & Lingkungan, 2018
Drag reducing polymers (DRP) is one of drag reducer types that is widely used in industry as an additive to improve fluid flow efficiency in pipes. This study is conducted to analyze the parameters that influence the efficiency of DRP through developing ...
Cindy Dianita   +2 more
doaj   +1 more source

Thermodynamic Effects in Hydrofoil and Inducer Cavitation

open access: yes, 2004
The present paper illustrates the main results of an experimental campaign conducted in the Thermal Cavitation Tuimel and in the CPRTF (Cavitating Pump Rotordynamic Test Facility) at CentrospazdAlta S.p.A.
BRAMANTI C   +3 more
core  

Gas-Liquid Two-Phase Flow in Up and Down Vertical Pipes [PDF]

open access: yes, 2013
Multiphase flows occurring in pipelines with a serpentine configuration is an important phenomenon, which can be encountered in heat exchangers used in a variety of industrial processes.
Almabrok, Almabrok Abushanaf
core  

Two-phase flow and pool boiling heat transfer in microgravity

open access: yes, 2010
Researches on two-phase flow and pool boiling heat transfer in microgravity, which included groundbased tests, flight experiments, and theoretical analyses, were conducted in the National Microgravity Laboratory/CAS. A semi-theoretical Weber number model
赵建福
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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