Results 41 to 50 of about 165,475 (261)

THE IMPACT OF GENDER DIVERSITY ON EARNINGS QUALITY OF LISTED FINANCIAL SERVICES FIRMS IN NIGERIA: ANALYSIS OF TWO-STAGE LEAST SQUARES

open access: yesGusau Journal of Accounting and Finance
This study investigates the impact of gender diversity on the earnings quality of listed financial service firms in Nigeria, focusing on the role of gender diversity and board size.
Joseph Olorunfemi Akande
doaj   +1 more source

An improved underwater TDOA/AOA joint localisation algorithm

open access: yesIET Communications, 2021
To solve the problem of sound source localisation in underwater sensor networks, this paper constructs a pseudo‐linear equation system of time difference of arrival and angle of arrival (TDOA/AOA) and then uses the weighted least squares algorithm to ...
Feng Jiang, Zhenkai Zhang
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

What Role Does Religion Have in Shaping Human Consumption?

open access: yesReligions, 2021
Religious belief, as an informal social institution, has a significant impact on all aspects of human civilization. Previous literature has studied the effects of religious belief on economic growth, income, education, etc.
Yugang He, Yinhui Wang, Xiaodan Gao
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Convex Combination of Ordinary Least Squares and Two-stage Least Squares Estimators

open access: yes, 2015
In the presence of confounders, the ordinary least squares (OLS) estimator is known to be biased. This problem can be remedied by using the two-stage least squares (TSLS) estimator, based on the availability of valid instrumental variables (IVs). This reduction in bias, however, is offset by an increase in variance.
Ginestet, Cedric E.   +2 more
openaire   +2 more sources

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

The hidden economic costs of air pollution in China: evidence from remotely sensed nighttime light data

open access: yesGIScience & Remote Sensing
While the negative health consequences of air pollution exposure are well documented, its effects on economic activities remain less understood. Existing empirical studies often focus on the impacts of air pollution on production-related economic ...
Han-Su Zhang   +7 more
doaj   +1 more source

Two-stage least squares as minimum distance [PDF]

open access: yesThe Econometrics Journal, 2019
SummaryThe two-stage least-squares (2SLS) instrumental-variables (IV) estimator for the parameters in linear models with a single endogenous variable is shown to be identical to an optimal minimum-distance (MD) estimator based on the individual instrument-specific IV estimators.
openaire   +3 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

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