Results 41 to 50 of about 1,088,529 (192)
Advanced Materials Technologies, EarlyView.Nanoporous silica nanoparticles incorporated in nanoporous platinum offer the possibility for implant‐associated drug delivery from neuronal electrodes. ABSTRACT Sensorineural hearing loss, resulting from damage to the hair cells of the inner ear, profoundly impairs quality of life.
Mosaieb Habib +10 more
wiley +1 more source
Advanced Materials Technologies, EarlyView.A patient‐specific, imaging‐guided aid enables precise and reproducible drug delivery to the inner ear. By guiding therapeutic agents directly to the round window niche, this approach reduces variability in drug localization, improves delivery safety, and addresses a critical bottleneck in inner ear therapy, offering a scalable strategy for precision ...
Yanjing Luo +4 more
wiley +1 more source
BiomoleculesThe tympanic membrane forms an impenetrable barrier between the ear canal and the air-filled middle ear, protecting it from fluid, pathogens, and foreign material entry.
Arwa Kurabi +4 more
doaj +1 more source
Brazilian Journal of Otorhinolaryngology, 2022 Introduction: Traumatic large tympanic membrane perforations usually fail to heal and require longer healing times. Few studies have compared the healing and hearing outcomes between gelatin sponge patching and ofloxacin otic solution.
Xiuguo Li, Hui Zhang, Yuanyuan Zhang
doaj +1 more source
Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration
Advanced Science, EarlyView.This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya +10 more
wiley +1 more source
Althea Medical Journal, 2016 Background: Tympanic membrane perforation is a hearing problem that has become a health problem in the society. In Indonesia, there are only a few studies regarding tympanic membrane perforation. This study was aimed to observe the frequency and clinical
Veronika Ratih +2 more
doaj +1 more source
TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss
Advanced Science, EarlyView.TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale +23 more
wiley +1 more source
Virtual Biopsy of Rat Tympanic Membrane Using Higher Harmonic Generation Microscopy
, 2011 Multiharmonic optical microscopy has been widely applied in biomedical research due to its unique capability to perform noninvasive studies of biomaterials.
LEE, WEN-JENG;LEE, CHIA-FENG;CHEN, SZU-YU;CHEN, YUH-SHYANG;SUN, CHI-KUANG +1 more
core +1 more source
Application of posterior canal skin flap for the repair of large tympanic membrane perforations
Laryngoscope Investigative Otolaryngology, 2022 Objective Many methods have been described for the repair of the tympanic membrane, but there is no general consensus as to the standard method. The aim of this study was to evaluate the effect of the inferior base posterior canal skin flap on the graft ...
Mohammad Faramarzi +3 more
doaj +1 more source
Review of the Molecular and Developmental Basis of Myhre Syndrome, Bench Research
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.ABSTRACT Myhre syndrome (MS) is a connective‐tissue disorder within the acromelic dysplasia spectrum. It is characterized by congenital craniofacial, skeletal, cutaneous anomalies, respiratory, cardiovascular along with intellectual disability, deafness, and progressive fibrosis.
Camille Viaut, Valerie Cormier‐Daire
wiley +1 more source