Results 51 to 60 of about 8,137 (207)

Consensus Guidelines for Diagnosis and Management of Pyruvate Dehydrogenase Complex Deficiency

Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Primary pyruvate dehydrogenase complex deficiency (PDCD) comprises a group of monogenic disorders caused by pathogenic variants in genes encoding subunits of, or regulatory components affecting, the pyruvate dehydrogenase complex. The clinical phenotype spans a broad continuum, ranging from early onset congenital lactic acidosis to infantile ...
Nandaki Keshavan, Julia Neugebauer, Marcello Bellusci, Enrico Bertini, Garry Brown, Niklas Darin, Suzanne DeBrosse, Lucy Drexler, Stefan Drexler, Gregory M. Enns, Rebecca D. Ganetzky, Kelly Gilbert, Austin Larson, Rebecca Legi, April N. Lehman, Camile Newby, Manuel Schiff, Rachel Skeath, Peter W. Stacpoole, Sarah Thompson, Emma Watt, Saskia B. Wortmann, Jirair K. Bedoyan, Shamima Rahman   +23 more
wiley   +1 more source

Correlation between tympanometry volume and three-dimensional computed tomography mastoid volumetry in tympanoplasty candidates

, 2021
Objective: Ventilation of the middle ear and mastoid air cells is believed to play an important role in the pathogenesis of chronic ear disease. Traditionally, ventilation is assessed by computed tomography.
Epprecht, L, Qingsong, L, Linder, T, Hashimi, S, Stenz, N   +4 more
core   +1 more source

Age‐Dependent Patterns of Cisplatin‐Induced Ototoxicity in Head and Neck Cancer: A Longitudinal Audiologic Analysis

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Background Cisplatin (CDDP) is a key chemotherapeutic agent used to treat head and neck cancer. Improved survival rates have increased concerns about CDDP‐induced ototoxicity, as this toxicity significantly impacts survivors' quality of life. However, the dose‐dependent and age‐related patterns of CDDP‐induced ototoxicity remain incompletely ...
C. Suzuki, Y. Kishimoto, M. Yamamoto, N. Yamamoto, M. Kitamura, S. Hiraoka, R. Nakashima, S. Morita, K. Omori   +8 more
wiley   +1 more source

Tympanometry and otoacoustic emissions in a cohort of special care neonates

, 1996
Otoacoustic emission (OAE) screening and oto-admittance testing (678 Hz probe tone) were performed on both ears of 84 special care neonates, as part of a larger study of middle-ear effusion in neonates and infants. OAE results, tympanometry, and acoustic
Sutton, G. J., Gleadle, P., Rowe, S. J.
core   +7 more sources

Occurrence of Sensorineural Hearing Loss in Viral Meningitis and Encephalitis

Journal of Medical Virology, Volume 98, Issue 10, October 2026.
ABSTRACT Hearing loss in viral neuroinfections is poorly investigated. The present study aimed to clarify if hearing loss can develop in viral meningitis and encephalitis. An OAE (oto‐acoustic emission) was measured in adult patients with viral meningitis and encephalitis on the day of admission and 30–60 days after discharge.
Elisa Skovgaard Jensen, Andreas Vestergaard Jensen, Per Cayé‐Thomasen, Pelle Trier Petersen, Birgitte Rønde Hansen, Nichlas Hovmand, Rannvá Winther, Jonas Bruun Kjærsgaard, Malene Kirchmann, Christian T. Brandt, DASGIB Study Group, Helene Mens, Birgitte Rønde Hansen, Hans Rudolf Lüttichau, Micha Jepsen, Christian Brandt, Christian Østergaard Andersen, Lykke Larsen, Merete Storgaard, Jacob Bodilsen, Henrik Nielsen   +20 more
wiley   +1 more source

High- and Low-Frequency Probe Tone Tympanometry in Chinese Infants [PDF]

, 2007
ObjectiveTo assess the utility of low- and high-frequency tympanometry in the diagnosis of middle ear dysfunction in Chinese infants.MethodsTympanograms were obtained with 226 Hz, 678 Hz and 1000 Hz probe tones from infants aged 5-25 weeks with normal ...
Shi-lin, Liu, Dao-feng, Ni, Ying-ying, Shang   +2 more
core   +1 more source

Frequency of Serous Otitis Media in Children without Otolaryngological Symptoms

International Archives of Otorhinolaryngology, 2017
Introduction Otitis media with effusion is the fluid in the middle ear with no signs or symptoms of acute ear infection. Objective This study aims to research the frequency of serous otitis media in patients referred to the pediatric clinic ...
Murat Kocyigit, Safiye Giran Ortekin, Taliye Cakabay, Guven Ozkaya, Selin Ustun Bezgin, Mustafa Kemal Adali   +5 more
doaj   +1 more source

Otovent Versus Valsalva: Physiological Insights for Diagnostic and Therapeutic Autoinflation in Eustachian Tube Dysfunction

Otolaryngology–Head and Neck Surgery, Volume 175, Issue 4, Page 867-873, October 2026.
Abstract Objectives Autoinflation aids assessment of Eustachian tube function, or as a conservative treatment for obstructive Eustachian tube dysfunction. This study compares the physiological characteristics of 2 autoinflation techniques, the Otovent® device and the Valsalva manoeuvre, to inform clinical application for both diagnosis and therapy ...
Kiran Joshi, Victor Lim, Victor Ho, James Tysome, Matthew Smith   +4 more
wiley   +1 more source

Dynamic Slow Motion Video Endoscopy as an Adjunct to Impedance Audiometry in the Assessment of Eustachian Tube Function

International Archives of Otorhinolaryngology, 2018
Introduction Eustachian tube (ET) dysfunction plays an important role not only in the pathophysiology of various middle ear disorders, but also in predicting the outcome of the treatment.
Sanoop E. Sanu, Shilpa Divakaran, Sabarinath Vijayakumar, Sunil Kumar Saxena, Arun Alexander, Suryanarayanan Gopalakrishnan   +5 more
doaj   +1 more source

Associations Between Antidiabetic Pharmacotherapy and Hearing Thresholds in Adult Hearing‐Impaired Patients With Type 2 Diabetes

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT Type 2 diabetes mellitus (T2DM) has increasingly been identified as a risk factor for sensorineural hearing loss, whereas the association between different antidiabetic therapies and hearing thresholds remains poorly characterized. This retrospective observational study evaluated 240 patients with T2DM and 105 normoglycemic controls who ...
Francesco Martines, Pietro Salvago, Francesca Vaccaro, Davide Vaccaro, Ginevra Malta, Fabiana Plescia, Stella Cascioferro, Gianluca Lavanco, Fulvio Plescia   +8 more
wiley   +1 more source