Results 81 to 90 of about 3,809 (218)

Possibilities of Inner Ear Barrier Models for Otologic Drug Development

open access: yesAdvanced Therapeutics, Volume 8, Issue 11, November 2025.
This review examines innovative organ chip models that reconstruct critical inner ear barriers, addressing a fundamental challenge in otologic drug development: the limited understanding of pharmaceutical behavior across these complex barriers. By replicating these barriers, the advanced models offer promising alternatives to traditional testing ...
Yeji Ahn   +7 more
wiley   +1 more source

Genome-wide association analysis reveals variants on chromosome 19 that contribute to childhood risk of chronic otitis media with effusion [PDF]

open access: yes, 2016
To identify genetic risk factors of childhood otitis media (OM), a genome-wide association study was performed on Finnish subjects, 829 affected children, and 2118 randomly selected controls.
Bhutta, Mahmood F.   +6 more
core   +1 more source

Preoperative Virtual Reality for Pediatric Patients Undergoing General Anesthesia: A Meta‐Analysis of Randomized Controlled Trial

open access: yesPediatric Anesthesia, Volume 35, Issue 11, Page 889-903, November 2025.
ABSTRACT Background Pediatric patients undergoing general anesthesia often face stress responses, anesthetic challenges, and delayed recovery. Virtual reality has emerged as a promising non‐pharmacological intervention, though its effectiveness varies across studies. This meta‐analysis evaluates the effects of preoperative virtual reality interventions
Difang Zhao, Ting Tian, Shuguang Jin
wiley   +1 more source

Targeting Neutrophil/Eosinophil Extracellular Traps by Aptamer‐Functionalized Nanosheets to Overcome Recalcitrant Inflammatory Disorders

open access: yesAdvanced Science, Volume 12, Issue 38, October 13, 2025.
In this study, C‐TAH, as multifunctional nanosheets, is developed with tannic acid and histone aptamer coverage. C‐TAH displays mild cytotoxicity, robust dsDNA and NETs/EETs binding efficiency, and potent antioxidant and antibacterial ability in vitro. C‐TAH treatment ameliorates dysregulated inflammation and restores hearing function in animal models,
Yongqiang Xiao   +13 more
wiley   +1 more source

The Outcome of Adenoidectomy and Tympa- nostomy Tube Insertion in Patients with Otitis Media with Effusion and Factor that Influences the Recurrence

open access: yesSiriraj Medical Journal, 2020
Objective: The adenoid is an important contributing factor for otitis media with effusion by serving as the reservoir for patho- genic bacteria. Adenoidectomy is suggested in the guidelines as an adjunctive surgical treatment for otitis media with ...
Kitirat Ungkanont
doaj  

Osseous hamartoma arising from the Eustachian tube

open access: yesClinics and Practice, 2013
A fairly quite rare case of osseous tumor arising from the Eustachian tube (ET) is described. A 56-year-old man presented with a smooth bulky mass in the nasopharynx and secretory otitis media in the right ear.
Ai Kawamoto   +5 more
doaj   +1 more source

Impact of swimming on chronic suppurative otitis media in Aboriginal children: a randomised controlled trial [PDF]

open access: yes, 2013
Objectives: To measure the impact of 4 weeks of daily swimming on rates of ear discharge among Aboriginal children with a tympanic membrane perforation (TMP) and on the microbiology of the nasopharynx and middle ear.Design, setting and participants: A ...
Leach, Amanda J.   +2 more
core   +1 more source

Denervation of the Eustachian Tube and Hearing Loss Following Trigeminal Schwannoma Resection

open access: yesJournal of Neurological Surgery Reports, 2016
Objectives To discuss eustachian tube dysfunction (ETD) as a cause of hearing loss and to discuss its pathogenesis following resection of trigeminal schwannomas.
Christopher J. Ito   +4 more
doaj   +1 more source

Does pneumococcal conjugate vaccine prevent otitis media? [PDF]

open access: yes, 2011
Yes, if the pneumococcal conjugate vaccine (PCV) series is given before 12 months of age. Vaccination before 12 months is associated with a statistically significant reduction in the incidence of both acute (AOM) and recurrent (ROM) otitis media ...
Fotinos, Charissa   +2 more
core  

Comparison of Outcome of Myringotomy Alone with Myringotomy and Tympanostomy Tube (Grommet) in Otitis Media with Effusion (OME)

open access: yesJournal of Rawalpindi Medical College, 2018
Background: To compare the outcome of myringotomy alone with myringotomy and tympanostomy tube (grommet) in otitis media with effusion (OME) in terms of improvement in hearing and tympanogram pattern.
Mudassar Ahmad Khan   +2 more
doaj  

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