Results 191 to 200 of about 19,606,378 (347)

The Role of TRPV1 in Type 1 Diabetes. [PDF]

Biology (Basel)
Silva-Picazo K, Allan ERO.
europepmc   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Correction: Development and recalibration of a multivariable type 1 diabetes prediction model for type 1 diabetes across multiple screening studies. [PDF]

BMC Med
Templeman EL, Ferrat LA, Parikh HM, You L, Triolo TM, Steck AK, Hagopian WA, Vehik K, Onengut-Gumuscu S, Gottlieb PA, Rich SS, Krischer JP, Redondo MJ, Oram RA, Type 1 diabetes TrialNet Study Group.   +14 more
europepmc   +1 more source

Cost-Effectiveness of Closed-Loop Automated Insulin Delivery Using the Cambridge Hybrid Algorithm in Children and Adolescents With Type 1 Diabetes: Results from a Multicenter 6-Month Randomized Trial [PDF]

D. Steven Fox, Julia Ware, Charlotte K. Boughton, Janet M. Allen, Malgorzata E. Wilinska, Martin Tauschmann, Louise Denvir, Ajay Thankamony, Fiona Campbell, R. Paul Wadwa, Bruce A. Buckingham, Nikki Davis, Linda A. DiMeglio, Nelly Mauras, Rachel Besser, Atrayee Ghatak, Stuart A. Weinzimer, Lauren Kanapka, Craig Kollman, Judy Sibayan, Roy W. Beck, Korey K. Hood, Roman Hovorka   +22 more
openalex   +1 more source

Plasma Beta-Glucuronidase Activity: A Novel Tool to Distinguish Type 1 from Type 2 Amiodarone-Induced Thyrotoxicosis? [PDF]

, 2019
Georgios Κ. Markantes, Marina Michalaki, George A. Vagenakis, Fotini N. Lamari, Efthymia Pitsi, Μαρία Ηλιοπούλου, Nicholas G. Beratis, Kostas B. Markou   +7 more
openalex   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Life stage transitions for people with type 1 diabetes. [PDF]

Lancet Diabetes Endocrinol
Vitale RJ, Toschi E, Ortega J, Munshi MN, Weinstock RS, Laffel LM, Kahkoska AR.   +6 more
europepmc   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Current status of primary hyperoxaluria type 1 in Japan. [PDF]

Urolithiasis
Ogawa T, Okamoto K, Yamamoto M, Sato Y, Ushijima K, Numahata D, Takeshita H, Inai H, Onozawa M, Miyazaki J, Takayama T.   +10 more
europepmc   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source